Evidence map›Paper›PMID 37857524›Full record

ArticleJournal for immunotherapy of cancer2023

Analysing the tumor transcriptome of prostate cancer to predict efficacy of Lu-PSMA therapy.

Analena Handke, Claudia Kesch, Wolfgang Peter Fendler, Tugce Telli, Yang Liu, Alexander Hakansson, Elai Davicioni, Jason Hughes, Hong Song, Katharina Lueckerath and 3 more

Abstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Variable cellular and radiobiological effects of [Journal of experimental & clinical cancer research : CR · 2026
    Article
  4. Article
  5. NeoadjuvantCancers · 2025
    Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Analena HandkeDepartment of Urology, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany analena.handke@web.de.ORCID 0009-0000-9472-8956
Claudia KeschDepartment of Urology, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany.
Wolfgang Peter FendlerDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany.
Tugce TelliDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany.
Yang LiuVeracyte, Inc, Decipher Biosciences Inc, Vancouver, BC, Canada.
Alexander HakanssonVeracyte, Inc, Decipher Biosciences Inc, Vancouver, BC, Canada.
Elai DavicioniVeracyte, Inc, Decipher Biosciences Inc, Vancouver, BC, Canada.
Jason HughesVeracyte, Inc, Decipher Biosciences Inc, Vancouver, BC, Canada.
Hong SongDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, Stanford University School of Medicine, Stanford, California, USA.
Katharina LueckerathDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany.
Ken HerrmannDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany.
Boris HadaschikDepartment of Urology, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany.
Robert SeifertDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationale

methodsBetween March 2018 and December 2021, a total of 168 patients were referred to

resultsIn the subset of patients who received

conclusionHigher PD-L2 signature might be associated with a better response to

Indexed as

Prostatic Neoplasms, Castration-ResistantRadioisotopesHumansMaleProstate-Specific AntigenRNATranscriptomeProstate-Specific AntigenRadioisotopesRNAProstatic NeoplasmsRadiotherapyTumor Biomarkers

Identifiers

PMID37857524
PMCPMC10603337

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.