Evidence map›Paper›PMID 37857502›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023

Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy.

Clara Diaz Garcia-Prada, Léna Carmes, Salima Atis, Ali Parach, Alejandro Bertolet, Marta Jarlier, Sophie Poty, Daniel Suarez Garcia, Wook-Geun Shin, Stanislas Du Manoir and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. In Vivo Studies of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  3. Article
  4. MHC-I-Driven Antitumor Immunity Counterbalances Low Absorbed Doses of Radiopharmaceutical Therapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Extracellular vesicles role in radio(nuclide)therapy.Journal of radiation research · 2024
    Review
  9. Metal-based nanoparticle in cancer treatment: lessons learned and challenges.Frontiers in bioengineering and biotechnology · 2024
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Clara Diaz Garcia-PradaInstitut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Léna CarmesInstitut Lumière Matière, Université Claude Bernard Lyon 1, Villeurbanne, France.
Salima AtisInstitut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Ali ParachInstitut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Alejandro BertoletDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Marta JarlierBiometrics Unit, Montpellier Cancer Institute, University of Montpellier, Montpellier, France; and.
Sophie PotyInstitut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Daniel Suarez GarciaDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Wook-Geun ShinDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Stanislas Du ManoirInstitut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France.
Jan SchuemannDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Olivier TillementInstitut Lumière Matière, Université Claude Bernard Lyon 1, Villeurbanne, France.
François LuxInstitut Lumière Matière, Université Claude Bernard Lyon 1, Villeurbanne, France.
Julie ConstanzoInstitut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France; jean-pierre.pouget@inserm.fr julie.constanzo@inserm.fr.
Jean-Pierre PougetInstitut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, Montpellier, France; jean-pierre.pouget@inserm.fr julie.constanzo@inserm.fr.
Inserm · FRInstitut de Recherche en Cancérologie de Montpellier · FRHarvard University · USMassachusetts General Hospital · USInstitut Lumière Matière · FRInstitut Universitaire de France · FRUniversité Claude Bernard Lyon 1 · FR

Funding

Radiation dosimetry for alpha-particle radiopharmaceutical therapy and application to pediatric neuroblastomaR00CA267560 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI BERTOLET REINA, ALEJANDRO · 2023 to 2025
$721k
NCI NIH HHS R00 CA267560
6 · The paper itself

Abstract

Ovarian cancer (OC) is the most lethal gynecologic malignancy (5-y overall survival rate, 46%). OC is generally detected when it has already spread to the peritoneal cavity (peritoneal carcinomatosis). This study investigated whether gadolinium-based nanoparticles (Gd-NPs) increase the efficacy of targeted radionuclide therapy using [

Indexed as

NanoparticlesOvarian NeoplasmsPeritoneal NeoplasmsAnimalsCell Line, TumorFemaleGadoliniumHumansLutetiumMiceRadioimmunotherapyRadioisotopesTissue DistributionTrastuzumabGadoliniumLutetiumRadioisotopesTrastuzumabAuger electronsovarian cancerradioimmunotherapyradiopharmaceuticalradiosensitizationTRT

Identifiers

PMID37857502
PMCPMC10690115
OpenAlexW4387772367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.