ArticleEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2023
Update of the molar incisor hypomineralization: Würzburg concept.
Article in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06727539 (Prevalence of Hypomineralized Second Primary Molars in a Group of Egyptian Children and Its Association with Molar-Incisor Hypomineralization), which is not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence of Hypomineralized Second Primary Molars in a Group of Egyptian Children and Its Association with Molar-Incisor Hypomineralization: a Cross-Sectional Study.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effectiveness of Various Pain Control Methods in Managing MIH-A Systematic Review and Meta-Analysis.International journal of paediatric dentistry · 2026Pooled it
- Evidence mapping and quality assessment of randomised trials related to molar incisor hypomineralisation.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Pooled it
- Effects of computer-assisted and conventional local anaesthesia on pain and anxiety in children with molar incisor hypomineralisation: a randomized controlled clinical trial.BMC oral health · 2026Trial
- Comparison of 2% lidocaine with epinephrine and 4% articaine with epinephrine in local anesthesia of maxillary molars affected by molar incisor hypomineralization: a randomized controlled trial.Scientific reports · 2026Trial
- Effectiveness of fissure sealants following different silver fluoride application protocols in MIH-affected molars: randomized clinical study.Clinical oral investigations · 2026Trial
- Comparative evaluation of remineralization agents in severe enamel hypomineralization using a porcine enamel model.BMC oral health · 2026Article
- Effect of Deproteinization on the Clinical Success of Composite Restorations in Molars Affected by Molar-Incisor Hypomineralization.Children (Basel, Switzerland) · 2026Article
- Prevalence, Severity and Treatment Needs of Molar Incisor Hypomineralization Among a Cohort of Lebanese Children: A Cross-Sectional Study.Children (Basel, Switzerland) · 2026Article
- Dental Rehabilitation Improves Oral Health-Related Quality of Life in Children with Molar-Incisor Hypomineralisation: A 12-Month Prospective Controlled Study.Children (Basel, Switzerland) · 2026Article
- Prevalence, clinical characteristics, and treatment needs of Molar Incisor Hypomineralization (MIH) in Turkish children: a cross-sectional study.BMC public health · 2026Article
- Generative Artificial Intelligence and Large Language Models in Paediatric Dentistry: A Scoping Review.International dental journal · 2026Article
- Prevalence and severity of molar incisor hypomineralization among children in Madinah, Saudi Arabia: A school-based cross-sectional study.BMC oral health · 2026Article
- Prevalence and etiology of molar incisor hypomineralization and hypomineralized second primary molars in children, Uşak Region, Turkey.BMC oral health · 2026Article
- Clinical management of severe molar-incisor hypomineralisation using CAD/CAM fabricated PMMA crowns: a case report.Biomaterial investigations in dentistry · 2026Article
- Management of molar-incisor hypomineralisation (MIH) with CAD/CAM indirect hybrid composite restorations in children: a retrospective observational case series.BMC oral health · 2025Observational
- Hypersensitivity associated with molar-incisor hypomineralisation (MIH) among elementary schoolchildren in Bavaria, Germany: results from a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Article
- The Remineralizing and Desensitizing Potential of Hydroxyapatite in Dentistry: A Narrative Review of Recent Clinical Evidence.Journal of functional biomaterials · 2025Review
- Shear Bond Strengths of Composite Resin Bonded to MIH-Affected Hard Tissues with Different Adhesives and Pre-Treatments.Dentistry journal · 2025Article
- COVID-19 and Its Aftermath on Pediatric Oral Health: A Study of Dental Caries and Hygiene in Romanian Children.Children (Basel, Switzerland) · 2025Article
- Efficiency of glass ionomer sealant application in reducing hypersensitivity in MIH-molars in schoolchildren immediately and after 12 weeks.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMolar incisor hypomineralization (MIH) is playing an increasingly important role in dental practice. MIH is defined as hypomineralization of systemic origin of one to four permanent first molars, often associated with affected incisors. Affected teeth are more susceptible to caries and post-eruptive enamel loss and should be diagnosed and treated as early as possible. In 2016, the Würzburg concept was developed for German-speaking countries including a classification index-the MIH Treatment Need Index (MIH-TNI)-and a treatment plan based on it for the use in daily practice. In the meantime, the concept has also gained international recognition. The aim of this paper is to update part 2 of the Würzburg concept, the treatment plan, as knowledge about MIH has increased and the disease has been studied more extensively in the last years. Other treatment approaches are now available and therefore need to be included in the concept. Although, the evidence of the different treatment options is still weak, practitioners need guidance in their daily practice.
methodsThe authors reviewed the available literature, including clinical and laboratory studies and published guidelines.
resultsThe updated version of the Würzburg concept includes additional non-invasive strategies and temporary therapy options, as well as treatment approaches for incisors. It therefore covers currently available treatment modalities for MIH-affected teeth, ranging from prophylaxis, non-invasive treatment to restorative approaches and possibly even extraction.
conclusionsThis is intended to help guide the practitioner and will need to be further validated by clinical trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.