Evidence map›Paper›PMID 37855934›Full record

ArticleAesthetic plastic surgery2024

Mapping the Vascular and Muscular Topography of the Glabellar Region: Implication for Improving Safety and Efficacy of the Glabellar Injections.

Abdul Veli Ismailoglu, Pelin Ismailoglu, Mustafa Aktekin

Abstract read
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Article in Aesthetic plastic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Abdul Veli IsmailogluDepartment of Anatomy, School of Medicine, Marmara University, Maltepe Basibuyuk Yolu, No:9, 34854, Maltepe, Istanbul, Turkey. abdulveli.ismailoglu@gmail.com.ORCID 0000-0003-0904-8679
Pelin IsmailogluFaculty of Health Sciences, Physiotherapy and Rehabilitation Program, Fenerbahce University, Ataturk Mah. Atasehir Bulvarı, Metropol Istanbul, 34758, Atasehir, Istanbul, Turkey.ORCID 0000-0002-2631-496X
Mustafa AktekinDepartment of Anatomy, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Kayisdagi cad, Kerem Aydinlar Kampusu, No: 32, 34752, Atasehir, Istanbul, Turkey.ORCID 0000-0003-4253-9963
Fenerbahçe University · TRKent Hastanesi · TRMaltepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBotulinum neurotoxin (BoNT) and filler injections into the highly vascularized glabellar region for aesthetical purposes are extremely common. Injections into the glabellar region without precise anatomical knowledge of its vascular and muscular topography may pose the risk of severe complications.

objectivesWe aimed to improve the safety and efficacy of the glabellar injections by mapping the regional muscles and vasculature in relation to the medial canthus and the defined reference lines.

methodsMeticulous dissection was performed to reveal glabellar region muscles and arteries under surgical microscope, in 16 hemifaces of whom arteries are injected with red-dyed latex. Location of the angular artery (AA) along with its branches was noted in relation to glabellar muscles.

resultsThe AA was always located superficial to the levator labii superioris alaeque nasi muscle (LLSAN) and then coursed toward the medial canthus to anastomose with the supratrochlear artery deep to the origin of the depressor supercilii (DS). The AA gave subcutaneously located central and paracentral branches coursing close to the mid-face line in 14 out of 16 hemifaces. Variable muscular connections were also present between the LLSAN, the DS and the procerus (P) muscles. No arteries were detected at the base of the medial eyebrow to which the DS, the P, and the frontalis (F) inserted.

conclusionsThis study provides a detailed map of muscular and vascular anatomy of the glabellar region to facilitate safe and efficient filler and BoNT injections without complications. NO LEVEL ASSIGNED: This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

CadaverFacial MusclesForeheadAdultAgedCosmetic TechniquesDermal FillersDissectionFemaleHumansInjections, IntramuscularMaleMiddle AgedRisk AssessmentSkin AgingDermal FillersAnatomyFillerGlabellaInjectionSafe

Identifiers

PMID37855934
OpenAlexW4387765145

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.