Trial reportWorld journal of urology2023
Thulium fiber laser vs Ho:YAG in RIRS: a prospective randomized clinical trial assessing the efficacy of lasers and different fiber diameters (150 µm and 200 µm).
Trial report in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.
- Rethinking high-frequency lithotripsy: a review by EAU endourology group.World journal of urology · 2026Pooled it
- Complications of thulium fiber laser lithotripsy: a systematic review and meta-analysis by the EAU-YAU endourology and urolithiasis working group.World journal of urology · 2026Pooled it
- Thulium fiber laser cauterization approach to congenital pyriform sinus fistula: a case series.Translational pediatrics · 2026Article
- Comparison of T-tilt, Trendelenburg, and dorsal lithotomy positions in retrograde intrarenal surgery: surgical, inflammatory, and efficiency outcomes.International urology and nephrology · 2026Article
- Adoption of thulium fiber laser for lithotripsy A scoping review and bibliometric analysis.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026Review
- Efficacy and safety of super-pulse thulium fiber laser compared to holmium: YAG laser for ureteral and renal stones: a multicenter retrospective study.Urolithiasis · 2025Article
- Does the use of a ureteral access sheath improve perioperative outcomes in ureteroscopy? A real-world multi-institutional study.Urolithiasis · 2025Article
- A Comparative Evaluation of Holmium:YAG and Thulium Fiber Lasers in Urinary Stone Treatment.Cureus · 2025Review
- Expanding urolithiasis treatment: comparison of super pulsed thulium laser and holmium:YAG laser for ureteral stone management.European journal of medical research · 2025Review
- Thulium fiber laser versus holmium:yttrium aluminum garnet for lithotripsy.World journal of urology · 2024Article
- Thulium fiber laser versus high-power holmium laser for renal stones: a systematic review and meta-analysis of high-quality studies.Therapeutic advances in urologyArticle
Corrections and comments
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Authors and funding
16 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aims of the study: (1) to compare the Super Pulse Thulium Fiber Laser (SP TFL) and the holmium: yttrium-aluminium-garnet (Ho:YAG) lasers in retrograde intrarenal surgery (RIRS); (2) to compare the efficacy of SP TFL laser fibers of different diameters (150 μm and 200 μm).
methodsA prospective randomized single-blinded trial was conducted. Patients with stones from 10 to 20 mm were randomly assigned RIRS in three groups: (1) SP TFL (NTO IRE-Polus, Russia) with fiber diameter of 150 μm; (2) SP TFL with 200-μm fiber; and (3) Ho:YAG (Lumenis, USA) with 200-μm fiber.
resultsNinety-six patients with kidney stones were randomized to undergo RIRS with SP TFL using a 150-μm fiber (34 patients) and a 200-μm fiber (32 patients) and RIRS with Ho:YAG (30 patients). The median laser on time (LOT) in the 200-μm SP TFL group was 9.2 (6.2-14.6) min, in 150-μm SP TFL-11.4 (7.7-14.9) min (p = 0.390), in Ho:YAG-14.1 (10.8-18.1) min (p = 0.021). The total energy consumed in 200-μm SP TFL was 8.4 (5.8-15.2) kJ; 150-μm SP TFL - 10.8 (7.3-13.5) kJ (p = 0.626) and in Ho:YAG-15.2 (11.1-25.3) kJ (p = 0.005).
conclusionsIrrespective of the density, RIRS with SP TFL laser has proven to be both a safe and effective procedure. Whilst the introduction of smaller fibers may have the potential to reduce the duration of surgery, SP TFL results in a reduction in the LOT and total energy for stone ablation in RIRS compared with Ho:YAG.
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