Evidence map›Paper›PMID 37855711›Full record

ArticleeLife2023

β-Arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor.

Carole Daly, Akim Abdul Guseinov, Hyunggu Hahn, Adam Wright, Irina G Tikhonova, Alex Rojas Bie Thomsen, Bianca Plouffe

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Beneath the surface: endosomal GPCR signaling.Trends in biochemical sciences · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Carole DalyWellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
Akim Abdul GuseinovSchool of Pharmacy, Queen's University Belfast, Belfast, United Kingdom.
Hyunggu HahnDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, United States.
Adam WrightWellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
Irina G TikhonovaSchool of Pharmacy, Queen's University Belfast, Belfast, United Kingdom.
Alex Rojas Bie ThomsenDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, United States.
Bianca PlouffeWellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.ORCID 0000-0002-8321-0796
Queen's University Belfast · GB

Funding

Spatiotemporal Regulation of GPCR Signaling by Different Beta-Arrestin ConformationsR35GM147088 · NIGMS · NEW YORK UNIVERSITY · PI Alex Rojas Bie Thomsen · 2022 to 2026
$2.0M
Regulation of Melanoma Cell Malignancy by Compartmentalized Chemokine Receptor SignalingR21CA243052 · NCI · NEW YORK UNIVERSITY · PI THOMSEN, ALEX ROJAS BIE · 2022 to 2022
$413k
Biotechnology and Biological Sciences Research Council BB/X002578/1NCI NIH HHS R21 CA243052NIGMS NIH HHS R35 GM147088Wellcome TrustWellcome Trust 215229/Z/19/Z
6 · The paper itself

Abstract

The vasopressin type 2 receptor (V

Indexed as

ArrestinsReceptors, Vasopressinbeta-Arrestin 1beta-ArrestinsEndosomesGTP-Binding ProteinsVasopressinsArrestinsbeta-Arrestin 1beta-ArrestinsGTP-Binding ProteinsReceptors, VasopressinVasopressinsarrestincell biologyendosomal signalingG proteinshumanmegaplexvasopressin type 2 receptor

Identifiers

PMID37855711
PMCPMC10586804
OpenAlexW4380488627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.