Evidence map›Paper›PMID 37855690›Full record

ArticleNucleic acids research2024

CaeNDR, the Caenorhabditis Natural Diversity Resource.

Timothy A Crombie, Ryan McKeown, Nicolas D Moya, Kathryn S Evans, Samuel J Widmayer, Vincent LaGrassa, Natalie Roman, Orzu Tursunova, Gaotian Zhang, Sophia B Gibson and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
7.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
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  8. A Male Expressed Copulatory Plug Increases Female Fertility inbioRxiv : the preprint server for biology · 2026
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  11. bioRxiv : the preprint server for biology · 2026
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  16. Global genomic diversity of the selfing nematodebioRxiv : the preprint server for biology · 2026
    Article
  17. Article
  18. Parasite defense covaries with reproductive timing, not with resistance.bioRxiv : the preprint server for biology · 2026
    Article
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Timothy A CrombieDepartment of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, FL, USA.ORCID 0000-0002-5645-4154
Ryan McKeownDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, USA.ORCID 0000-0003-3570-2494
Nicolas D MoyaDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-6817-1784
Kathryn S EvansDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-1388-8155
Samuel J WidmayerDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-1200-4768
Vincent LaGrassaNorthwestern University Information Technology, Media and Technology Innovation, Northwestern University, Evanston, IL USA.
Natalie RomanNorthwestern University Information Technology, Media and Technology Innovation, Northwestern University, Evanston, IL USA.
Orzu TursunovaNorthwestern University Information Technology, Media and Technology Innovation, Northwestern University, Evanston, IL USA.
Gaotian ZhangDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, USA.ORCID 0000-0001-6468-1341
Sophia B GibsonDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, USA.ORCID 0000-0001-9839-9045
Claire M BuchananDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, USA.ORCID 0000-0003-3725-3469
Nicole M RobertoDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-8339-0627
Rodolfo VieiraNorthwestern University Information Technology, Media and Technology Innovation, Northwestern University, Evanston, IL USA.
Robyn E TannyDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-0611-3909
Erik C AndersenDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0003-0229-9651
Northwestern University · USJohns Hopkins University · USFlorida Institute of Technology · US

Funding

Evolutionary Genetics of Animal DevelopmentR35GM141906 · NIGMS · NEW YORK UNIVERSITY · PI Matthew Rockman · 2021 to 2026
$2.6M
NIGMS NIH HHS R35 GM141906
6 · The paper itself

Abstract

Studies of model organisms have provided important insights into how natural genetic differences shape trait variation. These discoveries are driven by the growing availability of genomes and the expansive experimental toolkits afforded to researchers using these species. For example, Caenorhabditis elegans is increasingly being used to identify and measure the effects of natural genetic variants on traits using quantitative genetics. Since 2016, the C. elegans Natural Diversity Resource (CeNDR) has facilitated many of these studies by providing an archive of wild strains, genome-wide sequence and variant data for each strain, and a genome-wide association (GWA) mapping portal for the C. elegans community. Here, we present an updated platform, the Caenorhabditis Natural Diversity Resource (CaeNDR), that enables quantitative genetics and genomics studies across the three Caenorhabditis species: C. elegans, C. briggsae and C. tropicalis. The CaeNDR platform hosts several databases that are continually updated by the addition of new strains, whole-genome sequence data and annotated variants. Additionally, CaeNDR provides new interactive tools to explore natural variation and enable GWA mappings. All CaeNDR data and tools are accessible through a freely available web portal located at caendr.org.

Indexed as

CaenorhabditisDatabases, GeneticAnimalsCaenorhabditis elegansGenomeGenome-Wide Association StudyGenomics

Identifiers

PMID37855690
PMCPMC10767927
OpenAlexW4387764769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.