Evidence map›Paper›PMID 37855600›Full record

ArticleJournal of virology2023

Functional and transcriptional heterogeneity within the massively expanding HLADR

Prabhat Singh, Prashant Bajpai, Deepti Maheshwari, Yadya M Chawla, Keshav Saini, Elluri Seetharami Reddy, Kamalvishnu Gottimukkala, Kaustuv Nayak, Sivaram Gunisetty, Charu Aggarwal and 7 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. T Cell Responses During Dengue Infection.Current topics in microbiology and immunology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Prabhat Singh *ICGEB-Emory Vaccine Center, International Centre for Genetic Engineering and Biotechnology , New Delhi, India.
Prashant Bajpai *ICGEB-Emory Vaccine Center, International Centre for Genetic Engineering and Biotechnology , New Delhi, India.
Deepti MaheshwariICGEB-Emory Vaccine Center, International Centre for Genetic Engineering and Biotechnology , New Delhi, India.
Yadya M ChawlaICGEB-Emory Vaccine Center, International Centre for Genetic Engineering and Biotechnology , New Delhi, India.
Keshav SainiICGEB-Emory Vaccine Center, International Centre for Genetic Engineering and Biotechnology , New Delhi, India.ORCID 0000-0002-8072-2024
Elluri Seetharami ReddyICGEB-Emory Vaccine Center, International Centre for Genetic Engineering and Biotechnology , New Delhi, India.
Kamalvishnu GottimukkalaICGEB-Emory Vaccine Center, International Centre for Genetic Engineering and Biotechnology , New Delhi, India.
Kaustuv NayakICGEB-Emory Vaccine Center, International Centre for Genetic Engineering and Biotechnology , New Delhi, India.ORCID 0000-0002-7898-0294
Sivaram GunisettyDepartment of Pediatrics, Emory University School of Medicine, Emory University , Atlanta, Georgia, USA.
Charu AggarwalICGEB-Emory Vaccine Center, International Centre for Genetic Engineering and Biotechnology , New Delhi, India.
Shweta JainDepartment of Medicine, All India Institute of Medical Sciences , New Delhi, India.
Chaitanya VermaDepartment of Medicine, All India Institute of Medical Sciences , New Delhi, India.
Paras SinglaDepartment of Medicine, All India Institute of Medical Sciences , New Delhi, India.
Manish SonejaDepartment of Medicine, All India Institute of Medical Sciences , New Delhi, India.
Naveet WigDepartment of Medicine, All India Institute of Medical Sciences , New Delhi, India.ORCID 0000-0002-6603-601X
Kaja Murali-KrishnaICGEB-Emory Vaccine Center, International Centre for Genetic Engineering and Biotechnology , New Delhi, India.ORCID 0000-0002-6275-1710
Anmol ChandeleICGEB-Emory Vaccine Center, International Centre for Genetic Engineering and Biotechnology , New Delhi, India.ORCID 0000-0002-5702-7170
International Centre for Genetic Engineering and Biotechnology · INAll India Institute of Medical Sciences · INEmory University · US

Funding

Dengue Virus Infection in IndiaU01AI115651 · NIAID · EMORY UNIVERSITY · PI AHMED, RAFI · 2015 to 2019
$4.0M
Department of Biotechnology, Ministry of Science and Technology, India (DBT) BT/PR28416/MED/29/1310/2018HHS | National Institutes of Health (NIH) ICIDR 1UO1A/115654NIAID NIH HHS U01 AI115651
6 · The paper itself

Abstract

importanceCD8 T cells play a crucial role in protecting against intracellular pathogens such as viruses by eliminating infected cells and releasing anti-viral cytokines such as interferon gamma (IFNγ). Consequently, there is significant interest in comprehensively characterizing CD8 T cell responses in acute dengue febrile patients. Previous studies, including our own, have demonstrated that a discrete population of CD8 T cells with HLADR

Indexed as

CD8-Positive T-LymphocytesDengueCytokinesFeverHumansInterferon-gammaT-Lymphocyte SubsetsCytokinesInterferon-gammaCD8 T cellsdenguehumanIFNγ productiontranscriptomics

Identifiers

PMID37855600
PMCPMC10688317
OpenAlexW4387765209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.