Evidence map›Paper›PMID 37855260›Full record

ArticleJournal of cellular and molecular medicine2023

Integrin beta1 mediates the effect of telocytes on mesenchymal stem cell proliferation and migration in the treatment of acute lung injury.

Ruixue Qi, Jiayun Hou, Ying Yang, Zhicheng Yang, Lihong Wu, Tiankui Qiao, Xiangdong Wang, Dongli Song

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ruixue QiJinshan Hospital Center for Tumor Diagnosis & Therapy, Jinshan Hospital, Fudan University Shanghai Medical School, Shanghai, China.ORCID 0000-0002-9592-5772
Jiayun HouZhongshan Hospital, Department of Pulmonary and Critical Care Medicine, Institute of Clinical Science, Fudan University Shanghai Medical School, Shanghai, China.
Ying YangJinshan Hospital Center for Tumor Diagnosis & Therapy, Jinshan Hospital, Fudan University Shanghai Medical School, Shanghai, China.
Zhicheng YangJinshan Hospital Center for Tumor Diagnosis & Therapy, Jinshan Hospital, Fudan University Shanghai Medical School, Shanghai, China.
Lihong WuJinshan Hospital Center for Tumor Diagnosis & Therapy, Jinshan Hospital, Fudan University Shanghai Medical School, Shanghai, China.
Tiankui QiaoJinshan Hospital Center for Tumor Diagnosis & Therapy, Jinshan Hospital, Fudan University Shanghai Medical School, Shanghai, China.
Xiangdong WangJinshan Hospital Center for Tumor Diagnosis & Therapy, Jinshan Hospital, Fudan University Shanghai Medical School, Shanghai, China.ORCID 0000-0002-8406-7928
Dongli SongZhongshan Hospital, Department of Pulmonary and Critical Care Medicine, Institute of Clinical Science, Fudan University Shanghai Medical School, Shanghai, China.
Jinshan Hospital of Fudan University · CNShanghai Medical College of Fudan University · CN

Funding

Key Subject Construction Program of Shanghai Health Administrative Authority ZK2019B30Ministry of Education for Academic Special Science and Research Foundation for PhD Education 20130071110043National Key Research and Development Program 2016YFC0902400National Key Research and Development Program 2017YFC0909500National Key Research and Development Program 2017YFSF090207Operation funding of Shanghai Institute of Clinical BioinformaticsOriginal Research Personalized Support Project of Fudan University IDF152064/011Shanghai Engineering Research Center of Tumor Multi-Target Gene Diagnosis 20DZ2254300The National Nature Science Foundation of China 11410708600The National Nature Science Foundation of China 12431900207The National Nature Science Foundation of China 12JC1402200The National Nature Science Foundation of China 14431905100The National Nature Science Foundation of China 20JC1418200The National Nature Science Foundation of China 21140902600; 21ZR1412800; 21140902601The National Nature Science Foundation of China 81270099The National Nature Science Foundation of China 81270131The National Nature Science Foundation of China 81300010The National Nature Science Foundation of China 81320108001The National Nature Science Foundation of China 81700008The National Nature Science Foundation of China 81873409The National Nature Science Foundation of China 91230204Zhongshan Distinguished Professor Grant (XDW)
6 · The paper itself

Abstract

Co-transplantation of mesenchymal stem cells (MSCs) with telocytes (TCs) was found to have therapeutic effects, although the mechanism of intercellular communication is still unknown. Our current studies aim at exploring the potential molecular mechanisms of TCs interaction and communication with MSCs with a focus on integrin beta1 (ITGB1) in TCs. We found that the co-culture of MSCs with ITGB1-deleted TCs (TC

Indexed as

Acute Lung InjuryMesenchymal Stem CellsTelocytesCell ProliferationHumansIntegrin beta1LipopolysaccharidesLungPhosphatidylinositol 3-KinasesIntegrin beta1LipopolysaccharidesPhosphatidylinositol 3-Kinasesacute lung injuryintegrin beta1lungMSCsPI3Ktelocytes

Identifiers

PMID37855260
PMCPMC10746951
OpenAlexW4387765045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.