Evidence map›Paper›PMID 37855040›Full record

ReviewAmerican journal of physiology. Renal physiology2023

Delayed graft function post renal transplantation: a review on animal models and therapeutics.

Anne C S Barbosa, Lillian G Mauroner, Juhi Kumar, Sunder Sims-Lucas

Open access · greenAbstract readReview
In one paragraph

Review in American journal of physiology. Renal physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Proenkephalin A 119-159 in Kidney Transplantation: A Novel Biomarker for Superior Tracking of Graft Function Trajectories.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anne C S BarbosaDivision of Nephrology, Department of Pediatrics, University of Pittsburgh, UPMC Children's Hospital, Pittsburgh, Pennsylvania, United States.ORCID 0000-0002-4933-3426
Lillian G MauronerDivision of Nephrology, Department of Pediatrics, University of Pittsburgh, UPMC Children's Hospital, Pittsburgh, Pennsylvania, United States.
Juhi KumarDivision of Nephrology, Department of Pediatrics, University of Pittsburgh, UPMC Children's Hospital, Pittsburgh, Pennsylvania, United States.
Sunder Sims-LucasDivision of Nephrology, Department of Pediatrics, University of Pittsburgh, UPMC Children's Hospital, Pittsburgh, Pennsylvania, United States.ORCID 0000-0003-1908-4809
University of Pittsburgh · US

Funding

Regulation of Peroxisomal Metabolism by Lysine AcylationR01DK090242 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GOETZMAN, ERIC S · 2011 to 2024
$5.4M
VIRTUUS Children's Study: Validating Injury to the Renal Transplant Using Urinary Signatures in ChildrenR01HD091185 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI AMARAL, SANDRA, KEATING, BRENDAN JAMES · 2017 to 2021
$3.4M
The role of Sirtuin 5 in acute kidney injuryR01DK121758 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SIMS-LUCAS, SUNDER · 2020 to 2024
$2.3M
Dicarboxylic acid therapy for prevention of kidney injuryR01DK134346 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ERIC S GOETZMAN, Sunder Sims-Lucas · 2024 to 2026
$1.9M
Endothelial miR-17~92 protects against acute kidney injuryR01DK125015 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HO, JACQUELINE, SIMS-LUCAS, SUNDER · 2020 to 2023
$1.5M
Bone In CKD Alkali Response Pilot Trial (BICARb Pilot Trial)R01DK131811 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI KUMAR, JUHI, MELAMED, MICHAL L · 2022 to 2024
$1.0M
The University of Pittsburgh Summer Research Internship Program kidney workshop (SRIP-Kid)R25DK119180 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACQUELINE HO, Sunder Sims-Lucas · 2021 to 2026
$648k
NIDDK NIH HHS R01 DK090242NIDDK NIH HHS R01 DK121758NIDDK NIH HHS R01 DK125015NIDDK NIH HHS R01 DK131811NIDDK NIH HHS R01 DK134346NIDDK NIH HHS R25 DK119180
6 · The paper itself

Abstract

The incidence of end-stage renal disease (ESRD) has been increasing worldwide. Its treatment involves renal replacement therapy, either by dialyses or renal transplantation from a living or deceased donor. Although the initial mortality rates for patients on dialysis are comparable with kidney transplant recipients, the quality of life and long-term prognosis are greatly improved in transplanted patients. However, there is a large gap between availability and need for donor kidneys. This has led to the increase in the use of expanded kidney donor criteria. Allograft dysfunction immediately after transplant sets it up for many complications, such as acute rejection and shorter allograft survival. Delayed graft function (DGF) is one of the immediate posttransplant insults to the kidney allograft, which is increasing in prevalence due to efforts to maximize the available donor pool for kidneys and use of expanded kidney donor criteria. In this review, we discuss the risk factors for DGF, its implications for long-term allograft survival, animal models of DGF, and the therapeutic options currently under evaluation for prevention and management of DGF.

Indexed as

Kidney TransplantationAnimalsDelayed Graft FunctionGraft RejectionGraft SurvivalHumansModels, AnimalQuality of LifeRetrospective StudiesRisk Factorsacute kidney injurydelayed graft functionkidney transplanttherapeutics

Identifiers

PMID37855040
PMCPMC10878700
OpenAlexW4387765629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.