Evidence map›Paper›PMID 37855006›Full record

ArticleInternational journal of preventive medicine2023

Environmental Risk Factors for Pediatric Acute Leukemia: Methodology and Early Findings.

Pardis Nematollahi, Sina Arabi, Marjan Mansourian, Saeed Yousefian, Alireza Moafi, Sayed Nassereddin Mostafavi, Amirmansour Alavi Naeini, Afshin Ebrahimi, Karim Ebrahimpour, Mohammad Mehdi Amin and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of preventive medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. The Influence of DNA Repair Genes and Prenatal Tobacco Exposure on Risk of Childhood Acute Lymphoblastic Leukemia: A Gene-Environment Interaction Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Pardis NematollahiDepartment of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Sina ArabiApplied Physiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Marjan MansourianDepartment of Epidemiology and Biostatistics, School of Health, Isfahan university of medical sciences, Isfahan, Iran.
Saeed YousefianDepartment of pediatrics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Alireza MoafiDepartment of pediatrics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Sayed Nassereddin MostafaviDepartment of pediatrics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Amirmansour Alavi NaeiniDepartment of Community Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
Afshin EbrahimiDepartment of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.
Karim EbrahimpourDepartment of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.
Mohammad Mehdi AminDepartment of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.
Aryan KavoshDepartment of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Niayesh RadfarDepartment of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Azar NaimiDepartment of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Roya KelishadiDepartment of pediatrics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Isfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute leukemia is the most common type of malignancy in children, and no major environmental risk factors have been identified relating to its pathogenesis. This study has been conducted with the aim for identifying risk factors associated with this disease. Methods: This study was conducted in 2016-2020 among children aged <15 years residing in Isfahan Province, Iran. Children with newly diagnosed Acute lymphoblastic leukemia, including Acute myeloid leukemia (ALL and AML) were considered a case group. The control group was selected among children hospitalized in orthopedic and surgery wards in the same region. Demographic data, parental occupational exposures and educational level, maternal obstetric history, type of feeding during infancy and parental smoking habits, exposure to pesticides, and hydrocarbons besides dietary habits (using a food frequency questionnaire) were evaluated. Results: Overall, 497 children (195 cases and 302 controls) completed the survey. In the initial analysis, there was no significant difference between case and control groups about type of milk feeding ( Conclusions: The results of this study can be helpful in better understanding the environmental risk factors involved in the incidence of acute leukemia. Future publications based on the analysis of the database created in the present study can lead to recognizing these factors. In addition, evaluating the effect of these factors on treatment outcomes is an important step in reducing the burden of the disease.

Indexed as

Epidemiologyhematologyleukemiapediatrics

Identifiers

PMID37855006
PMCPMC10580182
OpenAlexW4387765497

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.