Evidence map›Paper›PMID 37854571›Full record

ArticleBiomedical optics express2023

Adaptive balanced detection spectral domain optical coherence tomography.

David A Miller, Roman Kuranov, Hao F Zhang

Abstract read
In one paragraph

Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David A MillerDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.ORCID https://orcid.org/0000-0002-1630-1233
Roman KuranovDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Hao F ZhangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.ORCID https://orcid.org/0000-0001-5089-1196

Funding

ER Stress and Diabetic RetinopathyR01EY019949 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ZHANG, SARAH X · 2010 to 2023
$5.5M
Clinical glaucoma management enabled by visible-light OCTU01EY033001 · NEI · NORTHWESTERN UNIVERSITY · PI SCHUMAN, JOEL S, ZHANG, HAO F · 2021 to 2025
$3.2M
In Vivo Function and Metabolism Evaluation of Glaucomatous RGCs by Two-Photon Scanning Laser OphthalmologyR01EY034353 · NEI · STANFORD UNIVERSITY · PI Yang Hu, Hao F Zhang · 2023 to 2026
$2.7M
Visible-light optical coherence tomography for clinical glaucoma managementR44EY026466 · NEI · OPTICENT, INC. · PI KURANOV, ROMAN · 2018 to 2023
$2.7M
Novel ocular imaging and molecular analysis of anterior eye segment for glaucomaR01EY034740 · NEI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Tsutomu Kume, Hao F Zhang · 2023 to 2026
$2.7M
Investigating nanoscale neuronal damages in early glaucoma towards clinical optical detectionR01EY029121 · NEI · NORTHWESTERN UNIVERSITY · PI LIU, XIAORONG, ZHANG, HAO F · 2018 to 2021
$2.0M
A Nanocarrier Platform for Targeting Schlemm's Canal CellsR01EY033813 · NEI · NORTHWESTERN UNIVERSITY · PI JOHNSON, MARK, SCOTT, EVAN ALEXANDER · 2022 to 2025
$1.9M
NEI NIH HHS R01 EY019949NEI NIH HHS R01 EY029121NEI NIH HHS R01 EY033813NEI NIH HHS R01 EY034353NEI NIH HHS R01 EY034740NEI NIH HHS R44 EY026466NEI NIH HHS U01 EY033001
6 · The paper itself

Abstract

Balanced detection optical coherence tomography (BD-OCT) enables near-shot noise-limited imaging by suppressing wavelength-dependent relative intensity noise (RIN) originating from the light source. In spectral-domain BD-OCT (SD-BD-OCT), the level of RIN suppression relies on the co-registration accuracy of the spectra simultaneously captured by two independent spectrometers. However, existing matching methods require careful pre-calibration using a RIN-dominated dataset or subjective post-processing using a signal-dominated dataset. We developed an adaptive subpixel matching approach, referred to as adaptive balance, that can be applied to any SD-BD-OCT dataset regardless of RIN or signal level without the need for pre-calibration. We showed that adaptive balance performed comparable to or better than reported methods by imaging phantoms with varying spectrometer camera gain, exposure time, and supercontinuum laser repetition rate. We further demonstrated the benefits of adaptive balance in human retinal imaging.

Identifiers

PMID37854571
PMCPMC10581816

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.