Photoacoustic tomography as a method to estimate the optical fluence distribution in turbid media.

Lawrence C M Yip, Elina Rascevska, Parsa Omidi, Jeffrey J L Carson

Abstract read

In one paragraph

Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lawrence C M YipLawson Health Research Institute, Imaging Program, 268 Grosvenor St., London, Canada, N6A 4V2, Canada.ORCID https://orcid.org/0000-0003-0014-8112

Elina RascevskaLawson Health Research Institute, Imaging Program, 268 Grosvenor St., London, Canada, N6A 4V2, Canada.ORCID https://orcid.org/0000-0003-0503-8078

Parsa OmidiWestern University, School of Biomedical Engineering, 1151 Richmond St, London, Canada, N6A 3K7, Canada.ORCID https://orcid.org/0000-0002-6694-8211

Jeffrey J L CarsonLawson Health Research Institute, Imaging Program, 268 Grosvenor St., London, Canada, N6A 4V2, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, there are no non-invasive experimental methods available for measuring optical fluence distributions in tissue. We present photoacoustic tomography (PAT) as a method to approximate the relative optical fluence distribution in a homogeneous optically scattering medium. Three-dimensional photoacoustic images were captured with a near-full view PAT scanner in phantoms with known optical absorption and scatter properties. Resultant 3D PAT images were compared to the expected optical fluence distributions from Monte Carlo simulations and diffusion theory using volumetric and shape analysis. Volumetric analysis of PAT images compared well with the optical fluence distributions from simulation. Dice similarity coefficients ranged from 51 to 82%. The reduced scattering coefficient estimated from PAT images compared well to estimates from simulations for values below 0.5 mm

Identifiers

PMID37854557

DOI10.1364/BOE.496078

PMCPMC10581793

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.