ArticleBiomedical optics express2023
Development and evaluation of a wearable peripheral vascular compensation sensor in a swine model of hemorrhage.
Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Peripheral perfusion noninvasive monitoring technologies - a literature and patent review.Journal of clinical monitoring and computing · 2026Review
- Impact of the β correction factor on the accuracy of speckle contrast imaging measurements.Biomedical optics express · 2026Article
- On-skin, micro-objective enabled camera module for speckle contrast optical spectroscopy/tomography.Biomedical optics express · 2025Article
- Compact and cost-effective laser-powered speckle contrast optical spectroscopy fiber-free device for measuring cerebral blood flow.Journal of biomedical optics · 2024Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Postpartum hemorrhage (PPH) is the leading and most preventable cause of maternal mortality, particularly in low-resource settings. PPH is currently diagnosed through visual estimation of blood loss or monitoring of vital signs. Visual assessment routinely underestimates blood loss beyond the point of pharmaceutical intervention. Quantitative monitoring of hemorrhage-induced compensatory processes, such as the constriction of peripheral vessels, may provide an early alert for PPH. To this end, we developed a low-cost, wearable optical device that continuously monitors peripheral perfusion via laser speckle flow index (LSFI) to detect hemorrhage-induced peripheral vasoconstriction. The measured LSFI signal produced a linear response in phantom models and a strong correlation coefficient with blood loss averaged across subjects (>0.9) in a large animal model, with superior performance to vital sign metrics.
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Registered trials
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