Evidence map›Paper›PMID 37854346›Full record

ArticleOTO open

Effect of Perioperative Antithrombotics on Postoperative Transfusion and Hematoma in Head and Neck Free Flaps.

Melanie D Hicks, Milind Vasudev, Jessica L Bishop, Natalie Garcia, Farshad Chowdhury, Tiffany T Pham, Gabriela Heslop, Benjamin Greene, Hari Jeyarajan, Jessica W Grayson and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in OTO open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Impact of intermittent pneumatic compression stockings on pulmonary embolism rates after laryngectomy: A retrospective Before-After comparative study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Melanie D HicksDepartment of Otolaryngology-Head and Neck Surgery University of Alabama at Birmingham Birmingham Alabama USA.ORCID 0000-0002-7162-3008
Milind VasudevSchool of Medicine University of California Irvine School of Medicine Irvine California USA.
Jessica L BishopDepartment of Otolaryngology-Head and Neck Surgery University of Alabama at Birmingham Birmingham Alabama USA.
Natalie GarciaSchool of Medicine University of Alabama at Birmingham Heersink School of Medicine Birmingham Alabama USA.
Farshad ChowdhuryDepartment of Otolaryngology-Head and Neck Surgery University of Alabama at Birmingham Birmingham Alabama USA.
Tiffany T PhamDepartment of Otolaryngology-Head and Neck Surgery University of Colorado School of Medicine Aurora Colorado USA.
Gabriela HeslopDepartment of Otolaryngology-Head and Neck Surgery University of Colorado School of Medicine Aurora Colorado USA.
Benjamin GreeneDepartment of Otolaryngology-Head and Neck Surgery University of Alabama at Birmingham Birmingham Alabama USA.
Hari JeyarajanDepartment of Otolaryngology-Head and Neck Surgery University of Alabama at Birmingham Birmingham Alabama USA.
Jessica W GraysonDepartment of Otolaryngology-Head and Neck Surgery University of Alabama at Birmingham Birmingham Alabama USA.
Julie A GoddardDepartment of Otolaryngology-Head and Neck Surgery University of Colorado School of Medicine Aurora Colorado USA.
Tjoson TjoaDepartment of Otolaryngology-Head and Neck Surgery University of California Irvine Irvine California USA.
Yarah HaidarDepartment of Otolaryngology-Head and Neck Surgery University of California Irvine Irvine California USA.
Carissa M ThomasDepartment of Otolaryngology-Head and Neck Surgery University of Alabama at Birmingham Birmingham Alabama USA.ORCID 0000-0003-0765-5731
University of Alabama at Birmingham · USUniversity of California, Irvine · USUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore if antiplatelet or anticoagulant therapy increases the risk of transfusion requirement or postoperative hematoma formation in patients undergoing microvascular reconstruction for head and neck defects. Study Design: Retrospective cohort study. Setting: Departments of Otolaryngology-Head and Neck Surgery at the University of Alabama at Birmingham, the University of Colorado, and the University of California Irvine. Methods: A multi-institutional, retrospective review on microvascular reconstruction of the head and neck between August 2013 to July 2021. Perioperative antithrombotic data were collected to examine predictors of postoperative transfusion and hematoma. Results: A total of 843 free flaps were performed. Preoperative hemoglobin, hematocrit, operative time, and flap type were positive predictors of postoperative transfusion in both bivariate ( Conclusion: Antithrombotic regimens do not increase the risk of postoperative transfusion or hematoma in head and neck microvascular reconstruction. Based on this limited data, perioperative antithrombotic regimens can be considered in patients who may otherwise be at risk for these postoperative complications.

Indexed as

antithromboticsfree flapsmicrovascular reconstructionpostoperative hematomapostoperative transfusion

Identifiers

PMID37854346
PMCPMC10580001
OpenAlexW4387708887

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.