Evidence map›Paper›PMID 37854305›Full record

ArticleAnesthesiology research and practice2023

Assessment of the Safety and Efficiency of a Preperitoneal Continuous Infusion Using Bupivacaine after Abdominal Laparotomy in Digestive Carcinology.

Hayat Ben-Saghroune, Mohammed Abdessadek, Sanae Achour, Youssef Kfal, Abderrahim El Bouazzaoui, Nabil Kanjaa, Hicham Sbai

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Anesthesiology research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07271979 (Liposomal Bupivacaine Versus Ropivacaine for Preperitoneal Infiltration Analgesia in Upper Abdominal Laparotomy), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07271979 nacompletednot on this mapstarted 2026, after this paper: background citation

Liposomal Bupivacaine Versus Ropivacaine for Preperitoneal Infiltration Analgesia in Upper Abdominal Laparotomy: A Randomized Controlled Trial

TypeinterventionalSponsorQilu Hospital of Shandong UniversityRan2026 to 2026Enrolled146ConditionsLiposomal Bupivacaine, Preperitoneal Infiltration, AnalgesiaArmsLiposomal bupivacaine, ropivacaine
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Hayat Ben-SaghrouneLaboratory of Anesthesia-Intensive Care and Emergency Medicine, Medical Center for Biomedical and Translational Research, Faculty of Medicine and Pharmacy, University Sidi Mohamed Ben Abdellah, Fez, Morocco.ORCID https://orcid.org/0000-0002-5682-1903
Mohammed AbdessadekLaayoune Higher School of Technology, Ibn Zohr University, Agadir, Morocco.ORCID https://orcid.org/0000-0002-9297-2493
Sanae AchourFaculty of Medicine and Pharmacy, Biomedical and Translational Research Laboratory University Sidi Mohammed Ben Abdellah, Pharmaco-Toxicology Department, Hassan II University Hospital, Fez, Morocco.
Youssef KfalCentral Medical Analysis Laboratory, Hassan II University Hospital, Fez, Morocco.
Abderrahim El BouazzaouiLaboratory of Anesthesia-Intensive Care and Emergency Medicine, Medical Center for Biomedical and Translational Research, Faculty of Medicine and Pharmacy, University Sidi Mohamed Ben Abdellah, Fez, Morocco.
Nabil KanjaaLaboratory of Anesthesia-Intensive Care and Emergency Medicine, Medical Center for Biomedical and Translational Research, Faculty of Medicine and Pharmacy, University Sidi Mohamed Ben Abdellah, Fez, Morocco.ORCID https://orcid.org/0000-0002-0983-4680
Hicham SbaiAnaesthesia and Critical Care Department, University Hospital of Tangier, Simulation Center Faculty of Medicine, University Abdelmalek Essadi, Tangier, Morocco.ORCID https://orcid.org/0000-0002-8762-4742
Centre Hospitalier Universitaire Hassan II · MASidi Mohamed Ben Abdellah University · MAAbdelmalek Essaâdi University · MAUniversité Ibn Zohr · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this paper is to evaluate the safety and efficacy of continuous preperitoneal wound infiltration using bupivacaine after abdominal laparotomy in relation to plasma bupivacaine concentration and visual analog scale. Our study was performed on 60 adult patients with digestive cancer, operated at laparotomy, and randomized into two groups: bupivacaine and saline groups. The wound infiltration was through a multiperforated catheter along the scar. For the bupivacaine group, 0.25% bupivacaine was used; however, for the saline group, only saline (0.9%) was infiltrated. The pain was assessed by using the visual analog scale (VAS) in both groups. Plasma bupivacaine concentration was measured by high-performance liquid chromatography. The bupivacaine group had significantly lower postoperative morphine consumption and lower postoperative pain than the saline group (

Identifiers

PMID37854305
PMCPMC10581849
OpenAlexW4387492114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.