Evidence map›Paper›PMID 37854025›Full record

ArticleTransplantation direct2023

Scandiatransplant Exchange Program (STEP): Development and Results From an International Kidney Exchange Program.

Ilse Duus Weinreich, Tommy Andersson, Margrét Birna Andrésdóttir, Mats Bengtsson, Alireza Biglarnia, Claus Bistrup, Line Boulland, Helle Bruunsgaard, Ilkka Helanterä, Kulli Kölvald and 6 more

Abstract read
In one paragraph

Article in Transplantation direct, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Long-term HLA-incompatible kidney transplant outcomes.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  3. Novel Allocation Strategies Can Boost Kidney Exchange Programs: A Monte Carlo Simulation.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  4. Kidney Transplantation in Western Balkans: A Regional Blueprint for Access, Capacity, and Equity.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  5. Article
  6. Access to kidney transplantation and re-transplantation from childhood to adulthood: long-term data from the ERA Registry.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Article
  7. Article
  8. Article
  9. Designing a kidney exchange program in Germany: simulations and recommendations.Central European journal of operations research · 2025
    Article
  10. Navigating a Quandary in Kidney Exchange Programs: A Review of Donor Travel versus Organ Shipment.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ilse Duus WeinreichScandiatransplant Office, Aarhus, Denmark.
Tommy AnderssonDepartment of Economics, Lund University, Lund, Sweden.
Margrét Birna AndrésdóttirDepartment of Nephrology, Landspitali University Hospital, Reykjavik, Iceland.
Mats BengtssonDepartment of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden.
Alireza BiglarniaDepartment of Nephrology, Skåne University Hospital, Malmö, Sweden.
Claus BistrupDepartment of Nephrology, Odense University Hospital, Odense, Denmark.
Line BoullandDepartment of Immunology and Transfusion Medicine, Oslo University Hospital, Oslo, Norway.
Helle BruunsgaardDepartment of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Ilkka HelanteräTransplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland.
Kulli KölvaldDepartment of Nephrology, Tartu University Hospital, Tartu, Estonia.
Jouni LauronenFinnish Red Cross Blood Service, Helsinki, Finland.
Jørn Petter LindahlDepartment of Transplant Medicine, Oslo University Hospital, Oslo, Norway.
Karin SkovDepartment of Renal Medicine, Aarhus University Hospital, Denmark.
Søren Schwarz SørensenDepartment of Nephrology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Lars WennbergDepartment of Transplantation Surgery, Karolinska University Hospital, Stockholm, Sweden.
Per LindnerTransplantation Centre, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0001-8672-6811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Kidney transplant candidates may be incompatible with their intended living donors because of the presence of antibodies against HLA and/or ABO. To increase the possibility of finding an acceptable kidney donor for these patients, the Scandiatransplant Exchange Program (STEP) program within Scandiatransplant was launched in 2019. Methods: This is a retrospective review of our experiences from the first 4 y of the STEP program, including details about the match runs, performed transplantations, and recipient outcomes within the program. Results: During 2019-2022, 11 match runs and 4 reruns were performed. In total, 114 pairs and 6 anonymous donors participated in these match runs. Fifty-one pairs (45%) participated in 1 match run, 31 pairs (27%) participated in 2 match runs, and 32 pairs (29%) participated in ≥3 match runs. Seventy-two individuals (63%) participated because of HLA incompatibility, 19 (17%) because of ABO incompatibility, and 7 (6%) because of both HLA and ABO incompatibility.Forty percent of the patients enrolled in the program underwent transplantation. In total, 49 transplantations have so far been performed within the program, and 46 (94%) of the recipients had a functioning kidney graft at follow-up in February 2023. Conclusions: The STEP program offers sensitized patients an enlarged pool of living donors and a chance of a compatible international living donor, resulting in an increased number of total transplantations. Currently, STEP is one of the largest transnational kidney exchange programs and has improved the situation for patients waiting for kidney transplantation in Scandiatransplant.

Identifiers

PMID37854025
PMCPMC10581625

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.