ArticleVeterinary medicine and science2023
Effects of two commercial diets and two supplements on urinary pH in dogs.
Article in Veterinary medicine and science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 2 citations in OpenAlex.
- Outcomes of medical dissolution for suspected struvite uroliths in dogs using a therapeutic multipurpose urinary diet and antimicrobial therapy.Journal of veterinary internal medicine · 2026Article
- Multiple contaminant detection in commercially available chicken-based cat kibbles in Italy.Frontiers in veterinary science · 2026Article
- Effects of two commercial diets and two supplements on urinary pH in dogs.Veterinary medicine and science · 2023Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUrinary pH manipulation by therapeutic foods or supplements is part of the treatment for urolithiasis. The effectiveness of these diets and supplements should be studied to determine which of these strategies is most effective. HYPOTHESIS/
objectivesTo assess the effect of the oral supplementation of potassium citrate, an ammonium chloride solution (Urical) and two dry therapeutic foods-Hill's® Prescription Diet® u/d® Canine (u/d diet) and Royal Canin® Urinary S/O dog (S/O diet)-on a dog's urinary pH at different time points over 8 h. ANIMALS: Seven healthy adult male research beagle dogs.
methodsA prospective interventional study lasting 31 days. The dogs either received a supplement (potassium citrate or rical) with a dry adult maintenance diet (control diet) or the therapeutic diet (u/d diet or S/O diet). Each treatment had a duration of 2-5 days, with 2- to 4-day washout periods in between. Urinary pH measurements were performed every 2 h between 07h00 and 15h00, with the food being given at 07h00 and 15h00, right after urine collection. The pH measurements obtained in each of the four treatments were compared to control (same dogs fed the control diet exclusively).
resultsWhen compared to the control diet at the same time points, biologically relevant changes in urinary pH (defined as ≥0.5) were: increase with potassium citrate at 7h00 and 13h00; increase with u/d diet at 9h00, 13h00, and 15h00; decrease with S/O diet at 9h00 and 11h00; Urical did not have a detectable effect on urinary pH. CONCLUSIONS AND CLINICAL IMPORTANCE: The present study confirms that therapeutic foods S/O and u/d, and potassium citrate supplement affected acid-base balance in healthy adult male beagle dogs, with the tested diets being more effective than the administered doses of the tested supplements at influencing urinary pH.
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