Evidence map›Paper›PMID 37853452›Full record

ArticleBMC chemistry2023

Green synthesis of highly functionalized heterocyclic bearing pyrazole moiety for cancer-targeted chemo/radioisotope therapy.

Kurls E Anwer, Galal H Sayed, Basma M Essa, Adli A Selim

Open access · goldAbstract read
In one paragraph

Article in BMC chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kurls E AnwerHeterocyclic Synthesis Lab, Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
Galal H SayedHeterocyclic Synthesis Lab, Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
Basma M EssaRadioactive Isotopes and Generators Department, Egyptian Atomic Energy Authority, Cairo, 13759, Egypt. Basmamohamed24@yahoo.com.
Adli A SelimLabelled Compounds Department, Egyptian Atomic Energy Authority, Cairo, 13759, Egypt.
Ain Shams University · EGEgyptian Atomic Energy Authority · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New derivatives of heterocyclic bearing pyrazole moiety were synthesized (eight new compounds from 2 to 9) via green synthesis methods (microwave-assisted and grinding techniques). 4,6-Diamino-1,3-diphenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile (2) shows high anti-cancer activity against both HepG2 and HCT-116 with IC

Indexed as

Dual cancer therapyGrindingMicrowavePyrazoleRadioiodination

Identifiers

PMID37853452
PMCPMC10585773
OpenAlexW4387738982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.