Evidence map›Paper›PMID 37853373›Full record

ArticleBMC psychiatry2023

The heart of Detroit study: a window into urban middle-aged and older African Americans' daily lives to understand psychosocial determinants of cardiovascular disease risk.

Kristin M Davis, Katherine Knauft, Lena Lewis, Michael Petriello, Lauren Petrick, Francesca Luca, Nataria T Joseph, Heather Fritz, Malcolm Cutchin, Lance Rappaport and 3 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Kristin M Davis *Department of Psychology, Wayne State University, 5057 Woodward Avenue, Detroit, MI, 48202, USA.
Katherine Knauft *Department of Psychology, Wayne State University, 5057 Woodward Avenue, Detroit, MI, 48202, USA.
Lena LewisCollege of Human Medicine, Michigan State University, East Lansing, MI, 48824, USA.
Michael PetrielloInstitute of Environmental Health Sciences, Department of Pharmacology, Wayne State University, Detroit, MI, 48201, USA.
Lauren PetrickDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Francesca LucaCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, 48201, USA.
Nataria T JosephDepartment of Psychology, Pepperdine University, Malibu, CA, 90265, USA.
Heather FritzSchool of Occupational Therapy, Pacific Northwest University of Health Sciences, Yakima, WA, 98901, USA.
Malcolm CutchinSchool of Occupational Therapy, Pacific Northwest University of Health Sciences, Yakima, WA, 98901, USA.
Lance RappaportDepartment of Psychology, University of Windsor, Windsor, ON, N9B 1B4, Canada.
Phillip LevyDepartments of Emergency Medicine and Physiology, Wayne State University, Detroit, MI, 48201, USA.
Christopher G EngelandDepartment of Biobehavioral Health, Pennsylvania State University, University Park, PA, 16802, USA.
Samuele ZilioliDepartment of Psychology, Wayne State University, 5057 Woodward Avenue, Detroit, MI, 48202, USA. fv0808@wayne.edu.
Wayne State University · USPacific Northwest University of Health Sciences · USIcahn School of Medicine at Mount Sinai · USMichigan State University · USPennsylvania State University · USPepperdine University · USUniversity of Windsor · CAWoodward (United States) · US

Funding

Untargeted Analysis ResourceU2CES030859 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ARORA, MANISH · 2019 to 2025
$8.2M
Stress and Cardiovascular Risk Among Urban African American Adults: A Multilevel, Mixed Methods Approach:SupplementR01HL153377 · NHLBI · WAYNE STATE UNIVERSITY · PI ZILIOLI, SAMUELE · 2021 to 2025
$3.3M
NHLBI NIH HHS R01 HL153377
6 · The paper itself

Abstract

backgroundCardiovascular disease disproportionately affects African Americans. Psychosocial factors, including the experience of and emotional reactivity to racism and interpersonal stressors, contribute to the etiology and progression of cardiovascular disease through effects on health behaviors, stress-responsive neuroendocrine axes, and immune processes. The full pathway and complexities of these associations remain underexamined in African Americans. The Heart of Detroit Study aims to identify and model the biopsychosocial pathways that influence cardiovascular disease risk in a sample of urban middle-aged and older African American adults.

methodsThe proposed sample will be composed of 500 African American adults between the ages of 55 and 75 from the Detroit urban area. This longitudinal study will consist of two waves of data collection, two years apart. Biomarkers of stress, inflammation, and cardiovascular surrogate endpoints (i.e., heart rate variability and blood pressure) will be collected at each wave. Ecological momentary assessments will characterize momentary and daily experiences of stress, affect, and health behaviors during the first wave. A proposed subsample of 60 individuals will also complete an in-depth qualitative interview to contextualize quantitative results. The central hypothesis of this project is that interpersonal stressors predict poor cardiovascular outcomes, cumulative physiological stress, poor sleep, and inflammation by altering daily affect, daily health behaviors, and daily physiological stress. DISCUSSION: This study will provide insight into the biopsychosocial pathways through which experiences of stress and discrimination increase cardiovascular disease risk over micro and macro time scales among urban African American adults. Its discoveries will guide the design of future contextualized, time-sensitive, and culturally tailored behavioral interventions to reduce racial disparities in cardiovascular disease risk.

Indexed as

Black or African AmericanCardiovascular DiseasesHeart Disease Risk FactorsRacismSocial Determinants of HealthAgedBiomarkersHuman ActivitiesHumansInflammationLongitudinal StudiesMichiganMiddle AgedRacial GroupsStress, PsychologicalUrban PopulationBiomarkersAfrican AmericansCardiovascular DiseaseCortisolEcologically momentary AssessmentInflammationMixed-Method ApproachRacismStress

Identifiers

PMID37853373
PMCPMC10585810
OpenAlexW4387734184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.