ArticleBMC medical research methodology2023
Comparative age-period-cohort analysis.
Article in BMC medical research methodology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- Trends in otitis media burden among BRICS from 1990 to 2023 and projections to 2040: an age-period-cohort analysis based on the 2023 global burden of disease study.Italian journal of pediatrics · 2026Article
- Incidence and mortality of nonmelanoma skin cancer in Europe: current trends and challenges.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Burden of Ovarian Cancer in China Attributable to Asbestos Exposure During 1990-2021 and the Projections Through 2050.International journal of women's health · 2026Article
- The Burden of Parkinson's Disease Based on the GBD 2021.International journal of public health · 2026Article
- Trends and projections of ischemic heart disease burden in the Belt and Road countries and China from 1990 to 2021: a study based on the 2021 global burden of disease.Annals of medicine · 2025Article
- Comprehensive age-period-cohort analysis of global pancreatitis burden and socioeconomic disparities (1990-2021).BMC gastroenterology · 2025Article
- Global, regional and national level burden of bulimia nervosa from 1990 to 2021 and their projections to 2030: analysis of the global burden of disease study.Journal of eating disorders · 2025Article
- Article
- [Analysis of epidemiological trends from 1990 to 2021 of liver cancer in China].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Article
- Trends and predictive research on the global burden of ischemic heart disease from 1990 to 2021: an analysis of the Global Burden of Disease study 2021.Frontiers in public health · 2025Article
- The burden of attention deficit hyperactivity disorder and incidence rate forecast in China from 1990 to 2021.Frontiers in psychiatry · 2025Article
- Global, regional, and national temporal trends in prevalence, deaths and disability-adjusted life years for chronic pulmonary disease, 1990-2021: an age-period-cohort analysis based on the global burden of disease study 2021.Frontiers in medicine · 2025Article
- Temporal trend in non-melanoma skin cancer mortality in China, 1992-2021: an analysis for the global burden of disease study 2021.Frontiers in medicine · 2025Article
- Analysis and comparison of the trends in burden of intracerebral hemorrhage in China from 1990 to 2021: results from the 2021 Global Burden of Disease Study.Frontiers in neurology · 2025Article
- Analysis and prediction of disease burden related to opioid use disorder in China based on GBD 2021.Frontiers in public health · 2025Article
- Global burden, trends, and inequalities of gastric cancer attributable to high-sodium diets: a 30-year analysis and projections based on the global burden of disease 2021 study.Frontiers in nutrition · 2025Article
- Differences in global, regional, and national time trends in disability-adjusted life years for atrial fibrillation and flutter, 1990-2019: an age-period-cohort analysis from the 2019 global burden of disease study.Frontiers in cardiovascular medicine · 2024Article
- Advances in statistical methods for cancer surveillance research: an age-period-cohort perspective.Frontiers in oncology · 2023Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCancer surveillance researchers analyze incidence or mortality rates jointly indexed by age group and calendar period using age-period-cohort models. Many studies consider age- and period-specific rates in two or more strata defined by sex, race/ethnicity, etc. A comprehensive characterization of trends and patterns within each stratum can be obtained using age-period-cohort (APC) estimable functions (EF). However, currently available approaches for joint analysis and synthesis of EF are limited.
methodsWe develop a new method called Comparative Age-Period-Cohort Analysis to quantify similarities and differences of EF across strata. Comparative Analysis identifies whether the stratum-specific hazard rates are proportional by age, period, or cohort.
resultsProportionality imposes natural constraints on the EF that can be exploited to gain efficiency and simplify the interpretation of the data. Comparative Analysis can also identify differences or diversity in proportional relationships between subsets of strata ("pattern heterogeneity"). We present three examples using cancer incidence from the United States Surveillance, Epidemiology, and End Results Program: non-malignant meningioma by sex; multiple myeloma among men stratified by race/ethnicity; and in situ melanoma by anatomic site among white women.
conclusionsFor studies of cancer rates with from two through to around 10 strata, which covers many outstanding questions in cancer surveillance research, our new method provides a comprehensive, coherent, and reproducible approach for joint analysis and synthesis of age-period-cohort estimable functions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.