Evidence map›Paper›PMID 37853279›Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2023

Troponin elevation as a marker of short deterioration and one-year death in a high-risk surgical patient cohort in a low and middle income country setting: a postoperative approach to increase surveillance.

Adriene Stahlschmidt, Sávio C Passos, Debora D Dornelles, Carisi Polanczyk, Claudia S Gutierrez, Rosangela R Minuzzi, Stela M J Castro, Luciana C Stefani, and the Ex-Care Collaborative

Registry-linked trialAbstract read
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In one paragraph

Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04187664 (Implementation of the Extended Care in High-Risk Surgical Patient), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04187664 naunknown statusnot on this map

Implementation of the Extended Care in High-Risk Surgical Patient (EXCARE) Pathway in High-risk Non-cardiac Surgical Population: Impact on Morbidity and 30-day Mortality

TypeinterventionalSponsorHospital de Clinicas de Porto AlegreRan2019 to 2021Enrolled1,720ConditionsPostoperative Complications, Patient Care TeamArmsPostoperative Monitoring, High-sensitivity cardiac troponin testing
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adriene StahlschmidtSchool of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Sávio C PassosSchool of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Debora D DornellesSchool of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Carisi PolanczykCardiology Service, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil.
Claudia S GutierrezAnaesthesia and Perioperative Medicine Service, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil.
Rosangela R MinuzziAnaesthesia and Perioperative Medicine Service, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil.
Stela M J CastroDepartment of Statistics, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
Luciana C StefaniSchool of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. lpstefani@hcpa.edu.br.ORCID http://orcid.org/0000-0002-3038-3108
and the Ex-Care Collaborative

Funding

FAPERGS PPSUS 2020FIPE - Hospital de Clinicas de Porto Alegre 2019-0066
6 · The paper itself

Abstract

purposeMyocardial injury after noncardiac surgery is common and mostly asymptomatic. The ideal target population that will benefit from routine troponin measurements in low and middle income countries (LMICs) is unclear. This study aims to evaluate the clinical outcomes of a cohort of high-risk surgical patients according to high-sensitivity troponin T (hsTnT) in an LMIC setting.

methodsWe conducted a prospective cohort study of 442 high-risk patients undergoing noncardiac surgery at a Brazilian hospital between February 2019 and March 2020. High-sensitivity troponin T levels were measured preoperatively, 24 hr, and 48 hr after surgery and stratified into three groups: normal (< 20 ng·L

resultsPostoperative myocardial injury occurred in 45% of patients. Overall, 30-day mortality was 8%. Thirty-day and one-year mortality were higher in patients with hsTnT ≥ 20 ng·L

conclusionThis study supports evidence that hsTnT is an important prognostic marker and a strong predictor of all-cause mortality after surgery. Troponin measurement in high-risk surgical patients could potentially be used as tool to scale-up care in LMIC settings. STUDY REGISTRATION: ClinicalTrials.gov (NCT04187664); first submitted 5 December 2019.

Indexed as

Developing CountriesTroponinBiomarkersHumansProspective StudiesRisk AssessmentTroponin TBiomarkersTroponinTroponin Thigh-risk surgical patienthigh-sensitivity troponinoutcome assessmentpostoperative carepostoperative complications/mortality

Identifiers

PMID37853279

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.