Evidence map›Paper›PMID 37851552›Full record

ArticleIEEE transactions on medical imaging2024

Zero-Shot Medical Image Translation via Frequency-Guided Diffusion Models.

Yunxiang Li, Hua-Chieh Shao, Xiao Liang, Liyuan Chen, Ruiqi Li, Steve Jiang, Jing Wang, You Zhang

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Review
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  10. A universal medical imaging modality translation model in brain and head-and-neck radiotherapy.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2026
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  13. Deep Learning for CT Synthesis in Radiotherapy.Bioengineering (Basel, Switzerland) · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. [Cross modal translation of magnetic resonance imaging and computed tomography images based on diffusion generative adversarial networks].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yunxiang Li
Hua-Chieh Shao
Xiao Liang
Liyuan Chen
Ruiqi Li
Steve Jiang
Jing Wang
You Zhang

Funding

Artificial Intelligence-Based Quality Assurance for Online Adaptive RadiotherapyR01CA258987 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Steve Bin Jiang, Dan Nguyen · 2022 to 2026
$2.8M
High-Precision Proton Therapy for Liver Cancer: Developing an End-to-end Strategy with Real-time Liver Tumor Localization and On-the-fly Plan Delivery AdaptationR01CA280135 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Weiguo Lu, You Zhang · 2024 to 2026
$1.8M
Accurate 4D Liver Tumor Localization for Radiotherapy using Contrast-Agent-Free X-ray Imaging and Liver Biomechanical ModelingR01CA240808 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI ZHANG, YOU · 2020 to 2024
$1.5M
NCI NIH HHS R01 CA240808NCI NIH HHS R01 CA258987NCI NIH HHS R01 CA280135
6 · The paper itself

Abstract

Recently, the diffusion model has emerged as a superior generative model that can produce high quality and realistic images. However, for medical image translation, the existing diffusion models are deficient in accurately retaining structural information since the structure details of source domain images are lost during the forward diffusion process and cannot be fully recovered through learned reverse diffusion, while the integrity of anatomical structures is extremely important in medical images. For instance, errors in image translation may distort, shift, or even remove structures and tumors, leading to incorrect diagnosis and inadequate treatments. Training and conditioning diffusion models using paired source and target images with matching anatomy can help. However, such paired data are very difficult and costly to obtain, and may also reduce the robustness of the developed model to out-of-distribution testing data. We propose a frequency-guided diffusion model (FGDM) that employs frequency-domain filters to guide the diffusion model for structure-preserving image translation. Based on its design, FGDM allows zero-shot learning, as it can be trained solely on the data from the target domain, and used directly for source-to-target domain translation without any exposure to the source-domain data during training. We evaluated it on three cone-beam CT (CBCT)-to-CT translation tasks for different anatomical sites, and a cross-institutional MR imaging translation task. FGDM outperformed the state-of-the-art methods (GAN-based, VAE-based, and diffusion-based) in metrics of Fréchet Inception Distance (FID), Peak Signal-to-Noise Ratio (PSNR), and Structural Similarity Index Measure (SSIM), showing its significant advantages in zero-shot medical image translation.

Indexed as

Cone-Beam Computed TomographyImage Processing, Computer-AssistedMagnetic Resonance ImagingPhantoms, ImagingSignal-To-Noise Ratio

Identifiers

PMID37851552
PMCPMC11000254

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.