Evidence map›Paper›PMID 37851393›Full record

Trial reportJournal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53

An Exposure-Based Cognitive-Behavioral Therapy for Youth with Severe Irritability: Feasibility and Preliminary Efficacy.

Reut Naim, Kelly Dombek, Ramaris E German, Simone P Haller, Katharina Kircanski, Melissa A Brotman

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Sex-Specific Associations of Irritability With Subcortical Brain Volumes.Biological psychiatry global open science · 2026
    Article
  6. Observational
  7. Targeting inhibitory control in youth irritability: challenges and opportunities.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Reut NaimSchool of Psychological Sciences, Tel-Aviv University.ORCID 0000-0002-0424-5094
Kelly DombekEmotion and Development Branch, National Institute of Mental Health.
Ramaris E GermanEmotion and Development Branch, National Institute of Mental Health.
Simone P HallerEmotion and Development Branch, National Institute of Mental Health.ORCID 0000-0002-5811-7442
Katharina KircanskiEmotion and Development Branch, National Institute of Mental Health.ORCID 0000-0002-6546-5584
Melissa A BrotmanEmotion and Development Branch, National Institute of Mental Health.ORCID 0000-0002-9859-4702
National Institute of Mental Health · JPTel Aviv University · IL

Funding

The Pathophysiology and Treatment Of Children With Severe Mood DysregulationZIAMH002786 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI LEIBENLUFT, ELLEN · 2009 to 2023
$34.0M
Unit on Neuroscience and Novel TherapeuticsZIAMH002969 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BROTMAN, MELISSA · 2019 to 2025
$13.8M
The Phenomenology And Neurophysiology Of Juvenile Bipolar DisorderZIAMH002778 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI LEIBENLUFT, ELLEN · 2009 to 2017
$10.8M
Intramural NIH HHS ZIA MH002778Intramural NIH HHS ZIA MH002786Intramural NIH HHS ZIA MH002969
6 · The paper itself

Abstract

objectiveClinically impairing irritability and temper outbursts are among the most common psychiatric problems in youth and present transdiagnostically; however, few mechanistically informed treatments have been developed. Here, we test the acceptability, feasibility, and preliminary efficacy of a novel exposure-based treatment with integrated parent management skills for youth with severe irritability using a randomized between-subjects multiple baseline design.

method

resultsNo patients dropped out once treatment began, and no adverse events were reported. Irritability symptoms improved during the active phase of treatment across all measurements (all

conclusionsResults support acceptability, feasibility, and preliminary efficacy of this novel treatment for youth with severe irritability. Limitations and future directions are also discussed.

Indexed as

Cognitive Behavioral TherapyFeasibility StudiesImplosive TherapyIrritable MoodAdolescentChildFemaleHumansMaleTreatment Outcome

Identifiers

PMID37851393
PMCPMC11024061
OpenAlexW4387728690

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.