Evidence map›Paper›PMID 37851127›Full record

ArticleLasers in medical science2023

Low-energy LED red light inhibits the NF-κB pathway and promotes hPDLSCs proliferation and osteogenesis in a TNF-α environment in vitro.

Yuan Liu, Juan Yang, Bing Jiang, Genzi Zheng, Yao Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Yuan Liu *Institute of Stomatology, Southwest Medical University, Luzhou, 646000, China.
Juan Yang *Oral & Maxillofacial Reconstruction and Regeneration of Luzhou Key Laboratory, Luzhou, 646000, China.
Bing JiangOral & Maxillofacial Reconstruction and Regeneration of Luzhou Key Laboratory, Luzhou, 646000, China.
Genzi ZhengOral & Maxillofacial Reconstruction and Regeneration of Luzhou Key Laboratory, Luzhou, 646000, China.
Yao WangInstitute of Stomatology, Southwest Medical University, Luzhou, 646000, China. 438730587@qq.com.ORCID http://orcid.org/0000-0001-8400-1665
Southwest Medical University · CNIntegrated Chinese Medicine (China) · CNXinqiao Hospital · CNYibin University · CN

Funding

Sichuan Province Medical Research Project S21015Sichuan science and technology plan joint innovation special task project 2022YFS0634University-level scientific research project of Southwest Medical University 2021ZKMS013
6 · The paper itself

Abstract

There are few studies on the effect of low-energy LED red light on periodontal tissue regeneration in an inflammatory environment. In this study, Cell Counting Kit-8 (CCK-8) assays were used to detect the effects of TNF-α at three different concentrations (0, 10 ng/ml, and 20 ng/ml) on the proliferation of human periodontal ligament stem cells (hPDLSCs), and 10 ng/ml was selected as the subsequent experimental stimulation concentration. CCK-8 assays were used to detect the effect of LED red light with energy density of 1 J/ cm

Indexed as

NF-kappa BTumor Necrosis Factor-alphaCell DifferentiationCell ProliferationCells, CulturedCore Binding Factor Alpha 1 SubunitHumansNF-KappaB Inhibitor alphaOsteogenesisPeriodontal LigamentCore Binding Factor Alpha 1 SubunitNF-kappa BNF-KappaB Inhibitor alphaTumor Necrosis Factor-alphahPDLSCsLED red lightNF-κBOsteogenic differentiationProliferationTNF-α

Identifiers

PMID37851127
OpenAlexW4387728934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.