Evidence map›Paper›PMID 37851109›Full record

ReviewLasers in medical science2023

Quantitative phase imaging for characterization of single cell growth dynamics.

Summiah Saleem Butt, Irum Fida, Maham Fatima, Muskan Saif Khan, Sonia Mustafa, Muhammad Noman Khan, Iftikhar Ahmad

Abstract readReview
PubMed Publisher
In one paragraph

Review in Lasers in medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Summiah Saleem ButtAlkhidmat Raazi Hospital, Rawalpindi, Pakistan.
Irum FidaThe Women University Multan, Multan, Pakistan.
Maham FatimaAlkhidmat Raazi Hospital, Rawalpindi, Pakistan.
Muskan Saif KhanAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Sonia MustafaSchool of Precision Instrument and Opto-electronics Engineering, Tianjin University, Tianjin, China.
Muhammad Noman KhanPhysics and Astronomy Department, Ohio University, Athens, OH, USA.
Iftikhar AhmadInstitute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar, Pakistan. iahmadmp@gmail.com.ORCID http://orcid.org/0000-0002-2377-5808

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quantitative phase imaging (QPI) has emerged as an indispensable tool in the field of biomedicine, offering the ability to obtain quantitative maps of phase changes due to optical path length delays without the need for contrast agents. These maps provide valuable information about cellular morphology and dynamics, unperturbed by the introduction of exogenous substances. In this review, a summary of recent studies that have focused on elucidating the growth dynamics of individual cells using QPI is presented. Specifically, investigations into cellular changes occurring during mitosis, the differentiation of cellular organelles, the assessment of distinct cell death processes (i.e., apoptosis, necrosis, and oncosis) and the precise measurement of live cell temperature are explored. Furthermore, the captivating applications of QPI in theragnostics, where its potential for transformative impact is prominently showcased, are highlighted. Finally, the challenges that need to be overcome for its wider adoption and successful integration into biomedical research are outlined.

Indexed as

ApoptosisCell DeathCell ProliferationApoptosisFluorescence microscopyInterferenceOptical phaseRefractive index

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.