Evidence map›Paper›PMID 37850761›Full record

SynthesisActa bio-medica : Atenei Parmensis2023

Adipose-derived stromal vascular fraction (SVF) for the treatment of androgenic alopecia (AGA): a systematic review.

Gian Piero Mantovani, Caterina Marra, Federico De Maria, Valentina Pinto, Giorgio De Santis

Abstract readSystematic Review
In one paragraph

Synthesis in Acta bio-medica : Atenei Parmensis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Recent Advances in Drug Development for Hair Loss.International journal of molecular sciences · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gian Piero MantovaniDepartment of Plastic and Reconstructive Surgery, Policlinico of Modena, University of Modena, Italy. gpieromanto@hotmail.com.
Caterina MarraDepartment of Plastic and Reconstructive Surgery, Policlinico of Modena, University of Modena, Italy. caterinamarra92@gmail.com.
Federico De MariaDepartment of Plastic and Reconstructive Surgery, Policlinico of Modena, University of Modena, Italy. demaria_federico@libero.it.
Valentina PintoDepartment of Plastic and Reconstructive Surgery, Policlinico of Modena, University of Modena, Italy. valentina.pinto@unimore.it.
Giorgio De SantisDepartment of Plastic and Reconstructive Surgery, Policlinico of Modena, University of Modena, Italy. giorgio.desantis@unimore.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimAndrogenetic alopecia (AGA) is a common chronic, hereditary, cutaneous and androgen-dependent condition. Low self-esteem and negatively impact quality of life are often consequences of AGA. Clinical treatment of AGA using SVF (Stromal vascular fraction) has been effective. In fact, hair follicle is affected by various environment factors and one of the most important factors is the vascularity of the scalp which is itself affected bySVF.

methodsDuring October 2022 we carried out a systematic review to identify all scientific publications discussing about hair loss treatment with stromal vascular fraction or adipose stem cell. We selected 140 articles. After screening process, we kept 9 articles complying with inclusion criteria.  Results: No serious adverse events were reported in all studies. Despite standardized protocol was not found, all studies reported a statistically significant increase in the number (density) of hair after SVF treatment. Two studies found a significant improvement at pull test. An increase of hair diameter was noticed after treatment. The combination between medical therapy and SVF proved to be advantageous.

conclusionsSVF is nowadays at the center of studies in the field of regenerative medicine due to its potential applications in many branches of medicine and surgery. The initial results are very promising but furthermore studies are necessary to establish a methodical and systematic research capable of demonstrating its real benefits and the creation of homogenous treatment protocols.

Indexed as

Quality of LifeStromal Vascular FractionAdipose TissueAlopeciaHairHumans

Identifiers

PMID37850761
PMCPMC10644943

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.