Evidence map›Paper›PMID 37850749›Full record

ArticleInfection and immunity2023

IL-23 receptor signaling licenses group 3-like innate lymphoid cells to restrict a live-attenuated oral Chlamydia vaccine in the gut.

Ying He, Yihui Wang, Rongze He, Ahmed Mohamed Abdelsalam, Guangming Zhong

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Quantifying Chlamydia in the Mouse Gastrointestinal Tract.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  2. Article
  3. Article
  4. Article
  5. Impact of oralmSystems · 2025
    Article
  6. Profile ofHuman vaccines & immunotherapeutics · 2025
    Article
  7. Infectivity of a pathogenicity-attenuatedInfection and immunity · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Ying HeDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio , San Antonio, Texas, USA.
Yihui WangDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio , San Antonio, Texas, USA.
Rongze HeDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio , San Antonio, Texas, USA.
Ahmed Mohamed AbdelsalamDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio , San Antonio, Texas, USA.
Guangming ZhongDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio , San Antonio, Texas, USA.ORCID 0000-0001-7053-5009
The University of Texas Health Science Center at San Antonio · US

Funding

MECHANISMS OF CHLAMYDIAL EVASION OF IMMUNE RECOGNATIONR01AI047997 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ZHONG, GUANGMING · 2000 to 2021
$6.9M
Chlamydia pathogenesisR56AI168279 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ZHONG, GUANGMING · 2022 to 2022
$571k
Genital Chlamydia spreading to the gastrointestinal tract promotes chlamydial pathogenicity in the upper genital tractR21AI151724 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ZHONG, GUANGMING · 2020 to 2021
$416k
NIAID NIH HHS R01 AI047997NIAID NIH HHS R21 AI151724NIAID NIH HHS R56 AI168279
6 · The paper itself

Abstract

An IFNγ-susceptible mutant of

Indexed as

Chlamydia InfectionsChlamydia muridarumAnimalsImmunity, InnateInterleukin-23LymphocytesMiceNuclear Receptor Subfamily 1, Group F, Member 3Vaccines, AttenuatedInterleukin-23Nuclear Receptor Subfamily 1, Group F, Member 3Vaccines, AttenuatedIFNγ+ILC3sIL-23 receptor signalingintrOvoral Chlamydia vaccine

Identifiers

PMID37850749
PMCPMC10652955
OpenAlexW4387729567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.