Evidence map›Paper›PMID 37850486›Full record

ArticleJournal of clinical laboratory analysis2023

Association between body roundness index and non-alcoholic fatty liver disease detected by Fibroscan in America.

Ningning Jiang, Shengguo Zhang, Jinguo Chu, Naibin Yang, Mingqin Lu

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ningning JiangDepartment of Internal Medicine, The Second Hospital of Ninghai City, Chengguan Hospital of Ninghai City, Ningbo, Zhejiang, China.
Shengguo ZhangDepartment of Infection, the Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jinguo ChuDepartment of General Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.ORCID https://orcid.org/0000-0002-5353-3420
Naibin YangDepartment of Hepatology and Infectious Diseases, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.ORCID https://orcid.org/0000-0001-7439-723X
Mingqin LuDepartment of Infectious Diseases, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.ORCID https://orcid.org/0000-0002-8331-5862
Ningbo University · CNWenzhou Medical University · CNNinghai County First Hospital · CN

Funding

TianQing Liver Diseases Research Fund Subject of Chinese Foundation for Hepatitis Prevention and Control TQGB20180358Zhejiang University and Ningbo First Hospital docking discipline general medicine to Jinguo Chu zd2020018
6 · The paper itself

Abstract

backgroundThe prevalence of non-alcoholic fatty liver disease (NAFLD) and obesity is worldwide on the rise. Body roundness index (BRI), as a newly developed anthropometric indicator, has been recently reported to identify obesity. However, it is still unclear whether BRI is associated with the prevalence of NAFLD.

methodsData were from the National Health and Nutrition Examination Survey (NHANES) 2017-2018. NAFLD was diagnosed based on hepatic steatosis defined by CAP values ≥274 dB/m. Multivariable logistic regression analysis was performed to detect the association between BRI and the odds of NAFLD. Subgroup analysis stratified by age, gender, BMI, and race was further conducted. To explore the potential ability of BRI in predicting NAFLD, the area under the curve (AUC) of BRI was calculated by receiver operating characteristic (ROC) analysis.

resultsAmong the 4467 study participants, 1718 (38.5%) were diagnosed with NAFLD. Compared to the non-NAFLD group, participants with NAFLD had a higher level of BRI. The positive associations between BRI and NAFLD were detected in all three models (mode 1: OR = 1.71, 95% CI: 1.65-1.78, p < 0.0001; mode 2: OR = 1.78, 95% CI: 1.71-1.86, p < 0.0001; mode3: OR = 1.23, 95% CI: 1.11-1.35, p < 0.0001). The positive association steadily existed in different subgroups after stratified by age, gender, and BMI. Moreover, the non-linear association between BRI and NAFLD was detected, presenting inverted U-shaped curves. Furthermore, BRI had a high predictive value (AUC = 0.807) in identifying NAFLD.

conclusionsBRI was positively associated with the prevalence of NAFLD among individuals in America, regardless of age, gender, and BMI. Besides, BRI presented a high ability for identifying NAFLD.

Indexed as

Non-alcoholic Fatty Liver DiseaseAnthropometryBody Mass IndexHumansNutrition SurveysObesitybody roundness indexcross-sectionalNAFLDNHANES

Identifiers

PMID37850486
PMCPMC10681427
OpenAlexW4387729044

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.