Evidence map›Paper›PMID 37850483›Full record

ArticleJournal of clinical apheresis2024

Therapeutic plasma exchange for mechanical red cell hemolysis: A case series.

Chloe E Douglas, Taylor R House, Larissa Yalon, Shina Menon

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of clinical apheresis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Neonatal continuous kidney replacement therapy.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chloe E DouglasDivision of Nephrology, Seattle Children's Hospital, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-0794-5205
Taylor R HouseDivision of Nephrology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0001-9370-1890
Larissa YalonDivision of Nephrology, Seattle Children's Hospital, Seattle, Washington, USA.
Shina MenonDivision of Nephrology, Seattle Children's Hospital, Seattle, Washington, USA.
Seattle Children's Hospital · USUniversity of Wisconsin–Madison · US

Funding

Pediatric Nephrology Training ProgramT32DK007662 · NIDDK · UNIVERSITY OF WASHINGTON · PI HINGORANI, SANGEETA · 1991 to 2020
$5.5M
RESEARCH TRAINING IN RENAL DISEASET32DK007467 · NIDDK · UNIVERSITY OF WASHINGTON · PI BANSAL, NISHA, KESTENBAUM, BRYAN R · 1986 to 2023
$5.1M
NIDDK NIH HHS T32 DK007467NIDDK NIH HHS T32 DK007662NIH HHS 5T32DK007467-40
6 · The paper itself

Abstract

We present three cases of severely elevated plasma free hemoglobin (PFH) in pediatric patients on mechanical circulatory support devices at a tertiary pediatric care center. Due to severe levels of PFH in the setting of critical illness with the inability to pursue immediate mechanical device exchange, membrane filtration therapeutic plasma exchange (TPE) was performed, which resulted in a lowering of PFH levels. However, long-term outcomes were heterogeneous across the cases. This case series reviews patient presentation, organ function before and after TPE, and the overall role of TPE as an effective treatment option to decrease severely elevated PFH levels. In doing so, we hope to add to what is known about the use of TPE for mechanical red cell hemolysis and provide guidance on its use in critically ill patients.

Indexed as

HemolysisPlasma ExchangeChildCritical IllnessHumansRetrospective StudiesTreatment Outcomemechanical red cell hemolysisplasma free hemoglobintherapeutic plasma exchange

Identifiers

PMID37850483
PMCPMC10922221
OpenAlexW4387728408

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.