Evidence map›Paper›PMID 37850464›Full record

ArticleJournal of the American Heart Association2023

Arterial Stiffness and Cardiorespiratory Fitness Impairment in the Community.

Matthew Nayor, Priya Gajjar, Patricia Miller, Venkatesh L Murthy, Ravi V Shah, Nicholas E Houstis, Raghava S Velagaleti, Martin G Larson, Ramachandran S Vasan, Gregory D Lewis and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Matthew NayorCardiovascular Medicine Section, Department of Medicine Boston University School of Medicine Boston MA USA.ORCID 0000-0002-6993-9396
Priya GajjarCardiovascular Medicine Section, Department of Medicine Boston University School of Medicine Boston MA USA.ORCID 0009-0002-2693-1578
Patricia MillerDepartment of Biostatistics Boston University School of Public Health Boston MA USA.ORCID 0000-0002-0141-717X
Venkatesh L MurthyDivision of Cardiovascular Medicine and Frankel Cardiovascular Center, Department of Medicine University of Michigan Ann Arbor MI USA.ORCID 0000-0002-7901-1321
Ravi V ShahVanderbilt Translational and Clinical Research Center, Cardiology Division Vanderbilt University Medical Center Nashville TN USA.ORCID 0000-0002-4471-7156
Nicholas E HoustisCardiology Division, Department of Medicine Massachusetts General Hospital, Harvard Medical School Boston MA USA.
Raghava S VelagaletiBoston University's and NHLBI's Framingham Heart Study Framingham MA USA.ORCID 0000-0002-2725-2692
Martin G LarsonBoston University's and NHLBI's Framingham Heart Study Framingham MA USA.ORCID 0000-0002-9631-1254
Ramachandran S VasanBoston University's and NHLBI's Framingham Heart Study Framingham MA USA.ORCID 0000-0001-7357-5970
Gregory D LewisCardiology Division, Department of Medicine Massachusetts General Hospital, Harvard Medical School Boston MA USA.ORCID 0000-0001-8108-8240
Gary F MitchellCardiovascular Engineering, Inc. Norwood MA USA.ORCID 0000-0001-5643-3145
Boston University · USHarvard University · USMichigan Medicine · USNorwood Hospital · USVanderbilt University Medical Center · US

Funding

THE FRAMINGHAM HEART STUDYN01HC25195 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAMACHANDRAN, VASAN S · 2007 to 2014
$83.8M
FRAMINGHAM HEART STUDY - YEAR 5 EXAM75N92019D00031 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAMACHANDRAN, VASAN · 2019 to 2024
$29.8M
Proteomic Profiling of Precise Exercise Pathophenotypes Across the HFpEF SpectrumR01HL131029 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Gregory Dyer Lewis, Matthew G. Nayor · 2016 to 2026
$7.7M
The Role of Histone Deacetylase 9 in Vascular CalcificationR01HL142809 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MALHOTRA, RAJEEV · 2018 to 2022
$4.0M
Metabolic Responses to an Oral Mixed Meal Tolerance Test: Intra-individual changes, correlates, and prognostic significanceR01HL156975 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI NAYOR, MATTHEW G. · 2021 to 2025
$3.3M
Molecular markers of early cardiometabolic health transitions in the CARDIA studyR01HL136685 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MURTHY, VENKATESH LOCHARLA, SHAH, RAVI · 2017 to 2021
$2.6M
Metabolic Signatures of Impaired Cardiorespiratory Fitness: Correlates, Prognostic Significance and Modulation with Exercise TrainingK23HL138260 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NAYOR, MATTHEW G. · 2017 to 2021
$998k
NHLBI NIH HHS 75N92019D00031NHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INHLBI NIH HHS K23 HL138260NHLBI NIH HHS N01HC25195NHLBI NIH HHS R01 HL131029NHLBI NIH HHS R01 HL136685NHLBI NIH HHS R01 HL142809NHLBI NIH HHS R01 HL156975
6 · The paper itself

Abstract

Background During exercise, a healthy arterial system facilitates increased blood flow and distributes it effectively to essential organs. Accordingly, we sought to understand how arterial stiffening might impair cardiorespiratory fitness in community-dwelling individuals. Methods and Results Arterial tonometry and maximum effort cardiopulmonary exercise testing were performed on Framingham Heart Study participants (N=2898, age 54±9 years, 53% women, body mass index 28.1±5.3 kg/m

Indexed as

Cardiorespiratory FitnessVascular StiffnessFemaleHumansMaleMiddle AgedObesityOxygenPulse Wave AnalysisOxygenarterial stiffnessexercisefitness

Identifiers

PMID37850464
PMCPMC10727403
OpenAlexW4387728469

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.