ArticleJournal of the American Heart Association2023
Stroke-Heart Syndrome: Does Sex Matter?
Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 10 citations in OpenAlex.
- Endophenotyping Without Anchors: Operational and Evidentiary Gaps in the Stroke-Heart Syndrome Framework.Cardiovascular drugs and therapy · 2026Article
- Genetic predisposition and mediating pathways in ischemic stroke-induced cardiac arrhythmias: a genome-wide analysis.Journal of advanced research · 2026Article
- Neurocardiology: Brain-Heart Interactions in the Heart.MedComm · 2026Review
- Stroke Heart Syndrome: Neuroimmune and Metabolic Crosstalk with Conceptual Approaches for Precision Therapeutics.Cardiovascular drugs and therapy · 2026Review
- Insights into the pathophysiology of stroke-heart syndrome: a review of recent literature and clinical trials to illuminate promising therapeutic strategies.Annals of medicine and surgery (2012) · 2026Article
- Albumin levels and risk of early cardiovascular complications after endovascular thrombectomy for acute ischaemic stroke.Scientific reports · 2026Article
- Sex-specific obesity paradox and type 2 myocardial infarction in acute ischemic stroke (AIS) patients.Biology of sex differences · 2026Article
- Stroke-heart syndrome and risk of incident dementia among patients with first-ever ischemic stroke: A territory-wide population-based cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Early Risk Prediction Model for Stroke-Heart Syndrome Following Endovascular Therapy.Aging and disease · 2025Article
- Sex Differences in Outcomes of Acute Myocardial Injury After Stroke.Journal of the American Heart Association · 2024Observational
- Rising Cardiac Troponin: A Prognostic Biomarker for Mortality After Acute Ischemic Stroke.Journal of the American Heart Association · 2024Article
- Cardiac Injury After Acute Ischemic Stroke: Are Women at Increased Risk?Journal of the American Heart Association · 2023Article
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
Background Cardiovascular complications after acute ischemic stroke (AIS) can be related to chronic/comorbid cardiac conditions or acute disruption of the brain-heart autonomic axis (stroke-heart syndrome). Women are known to be more vulnerable to certain stress-induced cardiac complications, such as Takotsubo cardiomyopathy. We investigated sex differences in cardiac troponin (cTn) elevation, cardiac events, and outcomes after AIS. Methods and Results We retrospectively analyzed consecutive patients with AIS from 5 stroke centers. Patients with AIS with elevated baseline cTn and at least 2 cTn measurements were included, while patients with acute comorbid conditions that could impact cTn levels were excluded. Poststroke acute myocardial injury was defined as the presence of a dynamic cTn pattern (rise/fall >20% in serial measurements) in the absence of acute atherosclerotic coronary disease (type 1 myocardial infarction) or cardiac death (type 3 myocardial infarction). From a total cohort of 3789 patients with AIS, 300 patients were included in the study: 160 were women (53%). Women were older, had a lower burden of cardiovascular risk factors, and more frequently had cardioembolic stroke and right insula involvement (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.