ArticleERJ open research2023
Clinical characteristics of chylothorax: results from the International Collaborative Effusion database.
Article in ERJ open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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Who cites it
13 citing papers in PubMed, 11 citations in OpenAlex.
- Chemical pleurodesis as a therapeutic option in non-traumatic chylothorax: a scoping review.Journal of thoracic disease · 2026Review
- An unusual case of chylothorax.Breathe (Sheffield, England) · 2026Article
- Aetiology, management and outcomes of eosinophilic pleural effusion: data from the International Multicentre Pleural Research Collaborative.ERJ open research · 2026Article
- Clinical outcomes of non-traumatic chylothorax at a Singapore tertiary referral hospital.BMJ open respiratory research · 2026Article
- Chronic Chylothorax in Childhood: Clinical Complexity and Management Challenges-A Case Report and Literature Overview.Diagnostics (Basel, Switzerland) · 2026Article
- [A case of chylothorax and chylous fistula following neck dissection with literature review].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026Review
- Article
- Practical therapeutic options for postoperative chylothorax.Journal of cardiothoracic surgery · 2026Article
- Article
- Chylothorax in Uncommon Contexts: Pulmonary Tuberculosis and Mantle Cell Lymphoma.Respirology case reports · 2025Article
- Superior Vena Cava Thrombosis Presenting As Massive Chylothorax: A Report of a Rare Case.Cureus · 2025Article
- Superimposed pleural infection in cirrhotic chylothorax.Respirology case reports · 2024Article
- Clinical overview of the physiology and pathophysiology of pleural fluid movement: a narrative review.ERJ open research · 2024Review
Corrections and comments
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Authors and funding
22 authors at 13 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chylothorax is an uncommon medical condition for which limited data are available regarding the contemporary aetiology, management and outcomes. The goal of this study was to better define these poorly characterised features. Methods: The medical records of adult patients diagnosed with chylothorax at 12 centres across Europe, America and South Africa from 2009-2021 were retrospectively reviewed. Descriptive and inferential statistics were performed. Results: 77 patients (median age 69 years, male to female ratio 1.5) were included. Subacute dyspnoea was the most typical presenting symptom (66%). The commonest cause of chylothorax was malignancy (68.8%), with lymphoma accounting for 62% of these cases. Other aetiologies were trauma (13%), inflammatory/miscellaneous conditions (11.7%) and idiopathic cases (6.5%). At the initial thoracentesis, the pleural fluid appeared milky in 73%, was exudative in 89% and exhibited triglyceride concentrations >100 mg·dL Conclusion: Chylothoraces have a poor prognosis and most require pleural interventions. Despite the standard recommendations, lymphatic imaging is seldom used, nor are dietary restrictions followed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.