Evidence map›Paper›PMID 37850162›Full record

ArticleBME frontiers2022

Blood-Brain Barrier Opening by Individualized Closed-Loop Feedback Control of Focused Ultrasound.

Chih-Yen Chien, Yaoheng Yang, Yan Gong, Yimei Yue, Hong Chen

Open access · diamondAbstract read
In one paragraph

Article in BME frontiers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Ultrasound-responsive composite hydrogels: Design rules for spatiotemporally controlled drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Brain-Targeting siRNA Delivery to Tackle Alzheimer's Disease.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chih-Yen ChienDepartment of Biomedical Engineering, Washington University in St. Louis, Saint Louis, Missouri 63130, USA.ORCID https://orcid.org/0000-0002-9529-2311
Yaoheng YangDepartment of Biomedical Engineering, Washington University in St. Louis, Saint Louis, Missouri 63130, USA.ORCID https://orcid.org/0000-0001-8952-887X
Yan GongDepartment of Biomedical Engineering, Washington University in St. Louis, Saint Louis, Missouri 63130, USA.ORCID https://orcid.org/0000-0003-0228-576X
Yimei YueDepartment of Biomedical Engineering, Washington University in St. Louis, Saint Louis, Missouri 63130, USA.
Hong ChenDepartment of Biomedical Engineering, Washington University in St. Louis, Saint Louis, Missouri 63130, USA.ORCID https://orcid.org/0000-0003-1904-0857
Washington University in St. Louis · US

Funding

Image-guided focused ultrasound-mediated intranasal brain drug delivery technique (FUSIN)R01EB027223 · NIBIB · WASHINGTON UNIVERSITY · PI Hong Chen · 2019 to 2026
$4.3M
Focused ultrasound-enabled brain tumor liquid biopsy (FUS-LBx) supplementR01EB030102 · NIBIB · WASHINGTON UNIVERSITY · PI Hong Chen · 2020 to 2026
$4.3M
FOCUS: FUNCTIONAL OPTICAL IMAGING FEEDBACK-CONTROLLED CELLULAR-LEVEL ULTRASOUND STIMULATIONR01MH116981 · NIMH · WASHINGTON UNIVERSITY · PI CHEN, HONG · 2018 to 2021
$2.8M
NIBIB NIH HHS R01 EB027223NIBIB NIH HHS R01 EB030102NIMH NIH HHS R01 MH116981
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID37850162
PMCPMC10521637
OpenAlexW4225003820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.