Evidence map›Paper›PMID 37850145›Full record

ArticleBiodesign research2022

Superior Conjugative Plasmids Delivered by Bacteria to Diverse Fungi.

Ryan R Cochrane, Arina Shrestha, Mariana M Severo de Almeida, Michelle Agyare-Tabbi, Stephanie L Brumwell, Samir Hamadache, Jordyn S Meaney, Daniel P Nucifora, Henry Heng Say, Jehoshua Sharma and 9 more

Open access · diamondAbstract read
In one paragraph

Article in Biodesign research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. ACS synthetic biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Ryan R CochraneDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.
Arina ShresthaDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.
Mariana M Severo de AlmeidaDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.
Michelle Agyare-TabbiDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada, N1G 2W1.
Stephanie L BrumwellDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.
Samir HamadacheDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.
Jordyn S MeaneyDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.
Daniel P NuciforaDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.
Henry Heng SayDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.
Jehoshua SharmaDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada, N1G 2W1.
Maximillian P M SoltysiakDepartment of Biology, The University of Western Ontario, London, Ontario, Canada, N6A 5B7.
Cheryl TongDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.
Katherine Van BeloisDepartment of Biology, The University of Western Ontario, London, Ontario, Canada, N6A 5B7.
Emma J L WalkerDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.
Marc-André LachanceDepartment of Biology, The University of Western Ontario, London, Ontario, Canada, N6A 5B7.
Gregory B GloorDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.
David R EdgellDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.
Rebecca S ShapiroDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada, N1G 2W1.
Bogumil J KarasDepartment of Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada, N6A 5C1.ORCID https://orcid.org/0000-0002-1199-4245
Western University · CAUniversity of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungi are nature's recyclers, allowing for ecological nutrient cycling and, in turn, the continuation of life on Earth. Some fungi inhabit the human microbiome where they can provide health benefits, while others are opportunistic pathogens that can cause disease. Yeasts, members of the fungal kingdom, have been domesticated by humans for the production of beer, bread, and, recently, medicine and chemicals. Still, the great untapped potential exists within the diverse fungal kingdom. However, many yeasts are intractable, preventing their use in biotechnology or in the development of novel treatments for pathogenic fungi. Therefore, as a first step for the domestication of new fungi, an efficient DNA delivery method needs to be developed. Here, we report the creation of superior conjugative plasmids and demonstrate their transfer via conjugation from bacteria to 7 diverse yeast species including the emerging pathogen

Identifiers

PMID37850145
PMCPMC10521675
OpenAlexW4294119635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.