Evidence map›Paper›PMID 37850002›Full record

ArticleKidney international reports2023

Patient Preferences for the Management of Gastrointestinal Symptoms in Kidney Transplantation: a Discrete Choice Experiment.

Tess E Cooper, Amy Dalton, Anh Kieu, Ryan Gately, Michael J Bourke, Jonathan C Craig, Rabia Khalid, Wai H Lim, Nicole Scholes-Robertson, Armando Teixeira-Pinto and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Kidney international reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Tess E CooperCochrane Kidney and Transplant, The Children's Hospital at Westmead, Australia.
Amy DaltonSydney School of Public Health, The University of Sydney, Australia.
Anh KieuCochrane Kidney and Transplant, The Children's Hospital at Westmead, Australia.
Ryan GatelyPrincess Alexandra Hospital, Australia.
Michael J BourkeWestmead Hospital, Australia.
Jonathan C CraigCochrane Kidney and Transplant, The Children's Hospital at Westmead, Australia.
Rabia KhalidSydney School of Public Health, The University of Sydney, Australia.
Wai H LimSir Charles Gairdner Hospital, Australia.
Nicole Scholes-RobertsonCochrane Kidney and Transplant, The Children's Hospital at Westmead, Australia.
Armando Teixeira-PintoSydney School of Public Health, The University of Sydney, Australia.
Allison JaureSydney School of Public Health, The University of Sydney, Australia.
Germaine WongSydney School of Public Health, The University of Sydney, Australia.
Martin HowellSydney School of Public Health, The University of Sydney, Australia.
The University of Sydney · AUChildren's Hospital at Westmead · AUFlinders University · AUThe University of Queensland · AUThe University of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Gastrointestinal (GI) symptoms in kidney transplant are common and debilitating. We aimed to ascertain patients' preferences for GI symptom management options to help future interventions align with treatment priorities. Methods: A discrete choice experiment was conducted with kidney transplant recipients in 3 Australian nephrology units. A multinomial logit model was used to quantify the preferences and trade-offs between 5 characteristics: cost, formulation, symptom burden, dietary changes, and medication quantities. Results: Seventy patients participated (mean age ± SD: 47 ± 15 years, 56% female), 57% had GI symptoms. Patients preferred interventions that will achieve complete resolution of GI symptoms compared to no improvement (odds ratio [95% confidence interval]: 15.3 [1.80, 129.50]), were delivered as a tablet rather than a sachet (1.6 [1.27, 2.08]), retained their current diet compared to eliminating food groups (6.0 [2.19, 16.27]), reduced medication burden (1.4 [1.06, 1.79]), and had lower costs (0.98 [0.96, 1.00]). Participants would be willing to pay AUD$142.20 [$83.90, $200.40] monthly to achieve complete resolution of GI symptoms or AUD$100.90 [$9.60, $192.10] to have moderate improvement in symptoms. Conclusions: Interventions that are highly effective in relieving all GI symptoms without the need for substantive dietary changes, and in tablet form, are most preferred by kidney transplant recipients.

Indexed as

chronic kidney diseasediscrete choice experimentgastrointestinal symptomskidney transplant

Identifiers

PMID37850002
PMCPMC10577360
OpenAlexW4385781346

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.