Evidence map›Paper›PMID 37849966›Full record

ReviewBME frontiers2020

Emerging Advances to Transform Histopathology Using Virtual Staining.

Yair Rivenson, Kevin de Haan, W Dean Wallace, Aydogan Ozcan

Abstract readReview
In one paragraph

Review in BME frontiers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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  14. AI-based computational H&E staining in lymphomas.Journal of hematopathology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yair RivensonElectrical and Computer Engineering Department, University of California, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0003-1132-0715
Kevin de HaanElectrical and Computer Engineering Department, University of California, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-7802-3857
W Dean WallaceDepartment of Pathology and Laboratory Medicine, Keck School of Medicine of USC, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-9850-9723
Aydogan OzcanElectrical and Computer Engineering Department, University of California, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-0717-683X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In an age where digitization is widespread in clinical and preclinical workflows, pathology is still predominantly practiced by microscopic evaluation of stained tissue specimens affixed on glass slides. Over the last decade, new high throughput digital scanning microscopes have ushered in the era of digital pathology that, along with recent advances in machine vision, have opened up new possibilities for Computer-Aided-Diagnoses. Despite these advances, the high infrastructural costs related to digital pathology and the perception that the digitization process is an additional and nondirectly reimbursable step have challenged its widespread adoption. Here, we discuss how emerging virtual staining technologies and machine learning can help to disrupt the standard histopathology workflow and create new avenues for the diagnostic paradigm that will benefit patients and healthcare systems alike via digital pathology.

Identifiers

PMID37849966
PMCPMC10521663

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.