Evidence map›Paper›PMID 37849753›Full record

ArticleFrontiers in immunology2023

Tumor-infiltrating CCR2

Joschka Bartneck, Ann-Kathrin Hartmann, Lara Stein, Danielle Arnold-Schild, Matthias Klein, Michael Stassen, Federico Marini, Jonas Pielenhofer, Sophie Luise Meiser, Peter Langguth and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Joschka BartneckIIIrd Department of Medicine - Hematology, Oncology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Ann-Kathrin HartmannIIIrd Department of Medicine - Hematology, Oncology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Lara SteinInstitute of Immunology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Danielle Arnold-SchildInstitute of Immunology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Matthias KleinInstitute of Immunology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Michael StassenInstitute of Immunology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Federico MariniInstitute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Jonas PielenhoferInstitute of Pharmaceutical and Biomedical Sciences of the Johannes Gutenberg-University, Biopharmaceutics and Pharmaceutical Technology, Mainz, Germany.
Sophie Luise MeiserInstitute of Pharmaceutical and Biomedical Sciences of the Johannes Gutenberg-University, Biopharmaceutics and Pharmaceutical Technology, Mainz, Germany.
Peter LangguthInstitute of Pharmaceutical and Biomedical Sciences of the Johannes Gutenberg-University, Biopharmaceutics and Pharmaceutical Technology, Mainz, Germany.
Matthias MackUniversity Hospital Regensburg, Department Nephrology, Regensburg, Germany.
Sabine MuthInstitute of Immunology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Hans-Christian ProbstInstitute of Immunology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Hansjörg SchildInstitute of Immunology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Markus Philipp RadsakIIIrd Department of Medicine - Hematology, Oncology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Johannes Gutenberg University Mainz · DEUniversity Hospital Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor development and progression is shaped by the tumor microenvironment (TME), a heterogeneous assembly of infiltrating and resident host cells, their secreted mediators and intercellular matrix. In this context, tumors are infiltrated by various immune cells with either pro-tumoral or anti-tumoral functions. Recently, we published our non-invasive immunization platform DIVA suitable as a therapeutic vaccination method, further optimized by repeated application (DIVA

Indexed as

MonocytesNeoplasmsCD8-Positive T-LymphocytesHumansImmunotherapyReceptors, CCR2T-Lymphocytes, CytotoxicTumor MicroenvironmentCCR2 protein, humanReceptors, CCR2cancer immunotherapyCCR2 monocytes +immune evasiontranscutaneous immunizationtumor micro environment (TME)

Identifiers

PMID37849753
PMCPMC10577317
OpenAlexW4387305235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.