Evidence map›Paper›PMID 37849565›Full record

ReviewCureus2023

Comprehensive Review of Red Meat Consumption and the Risk of Cancer.

Barath Prashanth Sivasubramanian, Mihir Dave, Viraj Panchal, Johnnie Saifa-Bonsu, Srujana Konka, Farahnaz Noei, Sanchitha Nagaraj, Umabalan Terpari, Priya Savani, Pratikkumar H Vekaria and 2 more

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  14. Transforming beef quality through healthy breeding: a strategy to reduce carcinogenic compounds and enhance human health: a review.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Barath Prashanth SivasubramanianInfectious Diseases, University of Texas Health Science Center at San Antonio, San Antonio, USA.
Mihir DaveInternal Medicine, Medical College Baroda, Vadodara, IND.
Viraj PanchalInternal Medicine, Smt. Nathiba Hargovandas Lakhmichand Municipal Medical College, Ahmedabad, IND.
Johnnie Saifa-BonsuInternal Medicine, University of Ghana Medical School, Accra, GHA.
Srujana KonkaInternal Medicine, Prathima Institute of Medical Sciences, Nagunur, IND.
Farahnaz NoeiInternal Medicine, University of Ottawa, Ottawa, CAN.
Sanchitha NagarajInternal Medicine, Ramaiah Medical College, Bengaluru, IND.
Umabalan TerpariInternal Medicine, Hospital Seri Manjung, Manjung, MYS.
Priya SavaniInternal Medicine, Surat Municipal Institute of Medical Education & Research, Surat, IND.
Pratikkumar H VekariaInternal Medicine, Prisma Health University Medical Group, Greenville, USA.
Vikramaditya Samala VenkataInternal Medicine, Cheshire Medical Center, Keene, USA.
Lokesh ManjaniInternal Medicine, MedStar Washington Hospital Center, Washington, USA.
MedStar Washington Hospital Center · USM.S. Ramaiah Medical College · INSir Sayajirao General Hospital Medical College · INSmt. N.H.L. Municipal Medical College · INUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Red and processed meat consumption rates are increasing in the United States. In this review, we present the current evidence that links red meat consumption and cancer development. A literature search was conducted in the PubMed and Google Scholar databases to review red meat consumption and its association with breast cancer and gastrointestinal cancer. Due to the presence of heme iron, which triggers oxidative reactions that eventually result in tumor formation, red meat consumption is strongly associated with the development of breast cancer. Ingestion of red meat increases Helicobacter pylori infections, resulting in enhanced expression of the CagA gene and the secretion of pro-inflammatory cytokines. This is the leading cause of gastric cancer. There is a strong correlation between heterocyclic amines and polycyclic aromatic hydrocarbons in red meat and the development of pancreatic cancer. However, additional research is necessary to confirm this finding. Adult colorectal cancer is caused by the formation of heterocyclic amines and DNA adducts due to the intake of red and processed meats cooked at higher temperatures. The consumption of poultry is associated with a reduced risk of breast and gastrointestinal cancers, but the results are inconsistent. The evidence is strong for the association between red meat and breast cancer and most gastric cancers. The presence of aromatic hydrocarbons, heterocyclic amines, and heme iron in red meat has been found to be behind tumorigenesis. Poultry has been shown to have a low association with cancer, but additional research is needed.

Indexed as

breast cancercolon cancergastrointestinal researchpancreatic cancerred meat

Identifiers

PMID37849565
PMCPMC10577092
OpenAlexW4386760336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.