Evidence map›Paper›PMID 37849352›Full record

ArticleJournal of veterinary internal medicine

Large T-cell extradural lymphoma with concurrent marked cerebrospinal fluid eosinophilia in a dog.

Anna M Massie, Katherine Skorupski, William Vernau, Ehren McLarty, Rachel V Brady, Karen M Vernau

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Anna M MassieDepartment of Clinical Sciences and Advanced Medicine, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-0598-4200
Katherine SkorupskiDepartment of Surgical and Radiological Sciences, University of California School of Veterinary Medicine, Davis, California, USA.
William VernauDepartment of Pathology, Microbiology and Immunology, University of California School of Veterinary Medicine, Davis, California, USA.
Ehren McLartyDepartment of Surgical and Radiological Sciences, University of California School of Veterinary Medicine, Davis, California, USA.
Rachel V BradyCell and Molecular Biology Graduate Program, Colorado State University, Fort Collins, Colorado, USA.
Karen M VernauDepartment of Surgical and Radiological Sciences, University of California School of Veterinary Medicine, Davis, California, USA.
University of California, Davis · USColorado State University · USUniversity of Pennsylvania · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Laura Marcu · 2002 to 2026
$84.9M
Biomedical Research Training for VeterinariansT32OD010437 · OD · COLORADO STATE UNIVERSITY · PI Gregg A Dean, KELLY S SANTANGELO · 2012 to 2026
$6.2M
NCI NIH HHS P30 CA093373NIH HHS T32 OD010437
6 · The paper itself

Abstract

A 3-year-old male pit bull terrier was presented for a 4-day history of progressive tetraparesis and cervical pain. Magnetic resonance imaging confirmed an extradural mass within the left lateral vertebral canal extending from caudal C5 to mid-T2. Lumbar cerebrospinal fluid (CSF) demonstrated marked (90%) eosinophilic inflammation. A C6-7 dorsal laminectomy and C7-T2 left hemilaminectomy were done, with gross disease remaining. Histopathology revealed a large T cell lymphoma with marked eosinophilic infiltration. The dog underwent CHOP-based chemotherapy with resolution of clinical signs, with a similar course of therapy performed at recurrence 37 months after initial presentation. The dog was euthanized 39 months after presentation for multiorgan failure secondary to neutropenic sepsis and aspiration pneumonia. This represents a positive long-term response to multimodal treatment of extradural T-cell lymphoma within the vertebral canal associated with a marked CSF eosinophilia.

Indexed as

Dog DiseasesEosinophiliaLymphoma, Non-HodgkinLymphoma, T-CellNeutropeniaAnimalsDogsMaleT-LymphocytesataxiaCHOPdecompressionneoplasia

Identifiers

PMID37849352
PMCPMC10658537
OpenAlexW4387729425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.