Evidence map›Paper›PMID 37849094›Full record

ArticlePhysical review. E2023

Interplay between morphology and competition in two-dimensional colony expansion.

Daniel W Swartz, Hyunseok Lee, Mehran Kardar, Kirill S Korolev

Abstract read
In one paragraph

Article in Physical review. E, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniel W SwartzDepartment of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Hyunseok LeeDepartment of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Mehran KardarDepartment of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Kirill S KorolevDepartment of Physics, Graduate Program in Bioinformatics and Biological Design Center, Boston University, Boston, Massachusetts 02215, USA.

Funding

Relationship between genealogies and biophysical processes during spatial growth.R01GM138530 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI KOROLEV, KIRILL SERGEEVICH · 2020 to 2024
$1.4M
NIGMS NIH HHS R01 GM138530
6 · The paper itself

Abstract

In growing populations, the fate of mutations depends on their competitive ability against the ancestor and their ability to colonize new territory. Here we present a theory that integrates both aspects of mutant fitness by coupling the classic description of one-dimensional competition (Fisher equation) to the minimal model of front shape (Kardar-Parisi-Zhang equation). We solve these equations and find three regimes, which are controlled solely by the expansion rates, solely by the competitive abilities, or by both. Collectively, our results provide a simple framework to study spatial competition.

Indexed as

Genetic FitnessGenetics, PopulationMutation

Identifiers

PMID37849094
PMCPMC11149782

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.