Evidence map›Paper›PMID 37849034›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2024

High-Affinity Host-Guest Recognition for Efficient Assembly and Enzymatic Responsiveness of DNA Nanostructures.

Raghu Pradeep Narayanan, Abhay Prasad, Alex Buchberger, Lei Zou, Julio Bernal-Chanchavac, Tara MacCulloch, Nour Eddine Fahmi, Hao Yan, Fei Zhang, Matthew J Webber and 1 more

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Crystalline Assemblies of DNA Nanostructures and Their Functional Properties.Angewandte Chemie (International ed. in English) · 2025
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Raghu Pradeep NarayananSchool of Molecular Sciences, Arizona State University, Tempe, AZ, 85287, USA.
Abhay PrasadSchool of Molecular Sciences, Arizona State University, Tempe, AZ, 85287, USA.
Alex BuchbergerSchool of Molecular Sciences, Arizona State University, Tempe, AZ, 85287, USA.
Lei ZouChemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA.
Julio Bernal-ChanchavacSchool of Molecular Sciences, Arizona State University, Tempe, AZ, 85287, USA.
Tara MacCullochSchool of Molecular Sciences, Arizona State University, Tempe, AZ, 85287, USA.
Nour Eddine FahmiBiodesign Center for Molecular Design and Biomimetics, Arizona State University, Tempe, AZ, 85287, USA.
Hao YanSchool of Molecular Sciences, Arizona State University, Tempe, AZ, 85287, USA.
Fei ZhangDepartment of Chemistry, Rutgers University-Newark, Newark, NJ, 07102, USA.
Matthew J WebberChemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA.
Nicholas StephanopoulosSchool of Molecular Sciences, Arizona State University, Tempe, AZ, 85287, USA.ORCID 0000-0001-7859-410X

Funding

Chemical synthesis of G protein-coupled receptors using sequential DNA-templated reactionsDP2GM132931 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI STEPHANOPOULOS, NICHOLAS · 2018 to 2018
$2.2M
Non-Covalent Molecular Recognition for Drug Targeting in the BodyR35GM137987 · NIGMS · UNIVERSITY OF NOTRE DAME · PI WEBBER, MATTHEW · 2020 to 2024
$2.2M
NIGMS NIH HHS DP2 GM132931NIGMS NIH HHS R35 GM137987NIH HHS DP2GM132931NIH HHS R35GM137987
6 · The paper itself

Abstract

The combination of multiple orthogonal interactions enables hierarchical complexity in self-assembled nanoscale materials. Here, efficient supramolecular polymerization of DNA origami nanostructures is demonstrated using a multivalent display of small molecule host-guest interactions. Modification of DNA strands with cucurbit[7]uril (CB[7]) and its adamantane guest, yielding a supramolecular complex with an affinity of order 10

Indexed as

AdamantaneNanofibersNanostructuresDNANanotechnologyAdamantaneDNADNA nanotechnologyhost-guest chemistrypeptide-DNA nanotechnologyself-assemblysupramolecular chemistry

Identifiers

PMID37849034
PMCPMC10922742

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.