ArticleInternational urology and nephrology2024
Development and internal validation of a nomogram predicting 3-year chronic kidney disease upstaging following robot-assisted partial nephrectomy.
Article in International urology and nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Robot-assisted partial nephrectomy for localized renal masses in elderly and younger patients: a systematic review and meta-analysis of perioperative outcomes.World journal of urology · 2025Pooled it
- Laparoscopic vs. Open nephrectomy for inflammatory renal conditions: a meta-analysis emphasizing safety.BMC urology · 2025Pooled it
- Effect of perioperative dexmedetomidine on acute kidney injury after partial nephrectomy: a single-centre, randomised, double-blind, placebo-controlled trial.British journal of anaesthesia · 2025Trial
- Impact of RoSCo-based preoperative risk stratification on early mobilization and short-term outcomes following robot-assisted laparoscopic partial nephrectomy for renal cell carcinoma: a single-center prospective study.Journal of robotic surgery · 2025Trial
- Preoperative prediction of preserved renal parenchymal volume via multilevel CT feature fusion: a proof-of-concept study.Abdominal radiology (New York) · 2026Article
- Bibliometric analysis of renal function preservation in robot-assisted partial nephrectomy: research trends, functional outcomes, and CKD-related perspectives.Journal of robotic surgery · 2026Review
- Application of a retrograde resection technique in robot-assisted laparoscopic nephron-sparing surgery for large complex renal tumors.Asian journal of urology · 2026Article
- Impact of 3D Virtual Modeling on Perioperative Outcomes in Robot-Assisted Partial Nephrectomy.Diagnostics (Basel, Switzerland) · 2026Article
- Acute kidney injury in urological conditions.Asian biomedicine : research, reviews and news · 2026Review
- The Effect of Dexmedetomidine on Postoperative Acute Kidney Injury in High-Risk Partial Nephrectomy Patients: A Retrospective Cohort Study.Drug design, development and therapy · 2026Article
- The Integration of Artificial Intelligence into Robotic Cancer Surgery: A Systematic Review.Journal of clinical medicine · 2025Review
- The predictive utility of the E-PASS score for postoperative complications in robot-assisted partial nephrectomy: a retrospective cohort study.BMC urology · 2025Observational
- Predicting hemorrhagic complications in robotic-assisted partial nephrectomy for renal tumors: simplifying risk assessment with tumor diameter and depth.Journal of robotic surgery · 2025Article
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- A Study of Adrenal Incidentaloma-Related Hormonal Assays After First Integration of the Diagnosis Within Primary Healthcare.Diseases (Basel, Switzerland) · 2025Article
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- Comparative outcomes of retroperitoneal partial nephrectomy for cT1 and cT2 renal tumors: a single-center experience.BMC urology · 2025Article
- Robot-assisted partial nephrectomy for renal cell carcinoma: A narrative review of different clinical scenarios.Asian journal of urology · 2025Review
Corrections and comments
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Authors and funding
20 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAim of the present study was to develop and validate a nomogram to accurately predict the risk of chronic kidney disease (CKD) upstaging at 3 years in patients undergoing robot-assisted partial nephrectomy (RAPN).
methodsA multi-institutional database was queried to identify patients treated with RAPN for localized renal tumor (cT1-cT2, cN0, cM0). Significant CKD upstaging (sCKD-upstaging) was defined as development of newly onset CKD stage 3a, 3b, and 4/5. Model accuracy was calculated according to Harrell C-index. Subsequently, internal validation using bootstrapping and calibration was performed. Then nomogram was depicted to graphically calculate the 3-year sCKD-upstaging risk. Finally, regression tree analysis identified potential cut-offs in nomogram-derived probability. Based on this cut-off, four risk classes were derived with Kaplan-Meier analysis tested this classification.
resultsOverall, 965 patients were identified. At Kaplan-Meier analysis, 3-year sCKD-upstaging rate was 21.4%. The model included baseline (estimated glomerular filtration rate) eGFR, solitary kidney status, multiple lesions, R.E.N.A.L. nephrometry score, clamping technique, and postoperative acute kidney injury (AKI). The model accurately predicted 3-year sCKD-upstaging (C-index 84%). Based on identified nomogram cut-offs (7 vs 16 vs 26%), a statistically significant increase in sCKD-upstaging rates between low vs intermediate favorable vs intermediate unfavorable vs high-risk patients (1.3 vs 9.2 vs 22 vs 54.2%, respectively, p < 0.001) was observed.
conclusionHerein we introduce a novel nomogram that can accurately predict the risk of sCKD-upstaging at 3 years. Based on this nomogram, it is possible to identify four risk categories. If externally validated, this nomogram may represent a useful tool to improve patient counseling and management.
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