ArticleScientific reports2023
Females exhibit smaller volumes of brain activation and lower inter-subject variability during motor tasks.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Influence of sex and systemic lupus erythematosus disease status on cerebral cortex structure.Lupus science & medicine · 2026Trial
- Subjective experience of listening to favorite songs and Murottal Al-Qur'an in young adult women: a quantitative EEG case series.Frontiers in behavioral neuroscience · 2026Article
- Reduced bilateral auditory cortex activation during pure-tone perception in pediatric HIV.Frontiers in neuroscience · 2026Article
- Sexual Dimorphisms in Neurodevelopment May Affect TBI Recovery in Pediatric Patients.Biomedicines · 2025Review
- The effects of taekwondo on depression symptoms and cognitive function: a systematic review and meta-analysis.Frontiers in sports and active living · 2025Review
- An objective neurophysiological study of subconcussion in female and male high school student athletes.Scientific reports · 2024Article
- Investigating female versus male differences in white matter neuroplasticity associated with complex visuo-motor learning.Scientific reports · 2024Article
- Sex differences in patterns of white matter neuroplasticity after balance training in young adults.Frontiers in human neuroscience · 2024Article
- Shared neural representation between motor execution and kinesthetic imagery in the primary motor cortex.Imaging neuroscience (Cambridge, Mass.)Article
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Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
Abstract
Past work has shown that brain structure and function differ between females and males. Males have larger cortical and sub-cortical volume and surface area (both total and subregional), while females have greater cortical thickness in most brain regions. Functional differences are also reported in the literature, yet to date little work has systematically considered whether patterns of brain activity indexed with functional magnetic resonance imaging (fMRI) differ between females and males. The current study sought to remediate this issue by employing task-based whole brain motor mapping analyses using an openly available dataset. We tested differences in patterns of functional brain activity associated with 12 voluntary movement patterns in females versus males. Results suggest that females exhibited smaller volumes of brain activation across all 12 movement tasks, and lower patterns of variability in 10 of the 12 movements. We also observed that females had greater cortical thickness, which is in alignment with previous analyses of structural differences. Overall, these findings provide a basis for considering biological sex in future fMRI research and provide a foundation of understanding differences in how neurological pathologies present in females vs males.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.