Evidence map›Paper›PMID 37848641›Full record

ArticleMolecular imaging and biology2024

Assessment of Brain Tumour Perfusion Using Early-Phase

Christian P Filss, Julian Cramer, Saskia Löher, Philipp Lohmann, Gabriele Stoffels, Carina Stegmayr, Martin Kocher, Alexander Heinzel, Norbert Galldiks, Hans J Wittsack and 7 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular imaging and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. The confounding effects of microvascular physiology on the uptake and diagnostic accuracy of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 3 countries.

Christian P FilssDepartment of Nuclear Medicine, RWTH University Hospital, Aachen, Germany. c.filss@fz-juelich.de.ORCID 0000-0002-9927-6335
Julian CramerInstitute of Neuroscience and Medicine (INM-3, INM-4, INM-5, INM-11), Forschungszentrum Jülich, Jülich, Germany.
Saskia LöherInstitute of Neuroscience and Medicine (INM-3, INM-4, INM-5, INM-11), Forschungszentrum Jülich, Jülich, Germany.
Philipp LohmannInstitute of Neuroscience and Medicine (INM-3, INM-4, INM-5, INM-11), Forschungszentrum Jülich, Jülich, Germany.
Gabriele StoffelsInstitute of Neuroscience and Medicine (INM-3, INM-4, INM-5, INM-11), Forschungszentrum Jülich, Jülich, Germany.
Carina StegmayrInstitute of Neuroscience and Medicine (INM-3, INM-4, INM-5, INM-11), Forschungszentrum Jülich, Jülich, Germany.
Martin KocherInstitute of Neuroscience and Medicine (INM-3, INM-4, INM-5, INM-11), Forschungszentrum Jülich, Jülich, Germany.
Alexander HeinzelDepartment of Nuclear Medicine, RWTH University Hospital, Aachen, Germany.
Norbert GalldiksInstitute of Neuroscience and Medicine (INM-3, INM-4, INM-5, INM-11), Forschungszentrum Jülich, Jülich, Germany.
Hans J WittsackDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University of Düsseldorf, Düsseldorf, Germany.
Michael SabelCenter of Integrated Oncology (CIO), University of Aachen, Bonn, Cologne and Düsseldorf, Germany.
Bernd NeumaierInstitute of Neuroscience and Medicine (INM-3, INM-4, INM-5, INM-11), Forschungszentrum Jülich, Jülich, Germany.
Jürgen ScheinsInstitute of Neuroscience and Medicine (INM-3, INM-4, INM-5, INM-11), Forschungszentrum Jülich, Jülich, Germany.
N Jon ShahInstitute of Neuroscience and Medicine (INM-3, INM-4, INM-5, INM-11), Forschungszentrum Jülich, Jülich, Germany.
Philipp T MeyerDepartment of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Felix M MottaghyDepartment of Nuclear Medicine, RWTH University Hospital, Aachen, Germany.
Karl-Josef LangenDepartment of Nuclear Medicine, RWTH University Hospital, Aachen, Germany.
Forschungszentrum Jülich · DEDüsseldorf University Hospital · DEHeinrich Heine University Düsseldorf · DEMaastricht University · NLUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMorphological imaging using MRI is essential for brain tumour diagnostics. Dynamic susceptibility contrast (DSC) perfusion-weighted MRI (PWI), as well as amino acid PET, may provide additional information in ambiguous cases. Since PWI is often unavailable in patients referred for amino acid PET, we explored whether maps of relative cerebral blood volume (rCBV) in brain tumours can be extracted from the early phase of PET using O-(2- PROCEDURE: Using a hybrid brain PET/MRI scanner, PWI and dynamic

resultsTBRs calculated from MR-rCBV and

conclusionEarly

Indexed as

Brain NeoplasmsGliomaMeningeal NeoplasmsHumansMagnetic Resonance ImagingPerfusionPositron-Emission TomographyTyrosineTyrosineAmino acid PETBrain tumourEarly FET PETGliomaO-(2-18F-Fluoroethyl)-L-tyrosinePWIrCBV

Identifiers

PMID37848641
PMCPMC10827807
OpenAlexW4387707690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.