ReviewJournal of perinatology : official journal of the California Perinatal Association2023
Alloimmune hemolytic disease of the fetus and newborn: genetics, structure, and function of the commonly involved erythrocyte antigens.
Review in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Rhesus Box as the Primary Mechanism of RHD Gene Deletion in RhD-Negative Blood Donors from Eastern Iran.International journal of hematology-oncology and stem cell research · 2026Article
- Microscopy-Based Methods for Measuring Platelet and Red Blood Cell Phagocytosis.Methods in molecular biology (Clifton, N.J.) · 2026Article
- [Rh blood group: Review and importance of genotyping].Revista medica del Instituto Mexicano del Seguro Social · 2026Review
- Hereditary Spherocytosis: Review of Presentation at Birth.Children (Basel, Switzerland) · 2025Article
- Red blood cell alloimmunization and pregnancy: Diagnosis and management.Pregnancy (Hoboken, N.J.) · 2025Review
- FcRn Blockade as a Targeted Therapeutic Strategy in Antibody-Mediated Autoimmune Diseases: A Focus on Warm Autoimmune Hemolytic Anemia.Antibodies (Basel, Switzerland) · 2025Review
- The MNS blood group system in Tunisian blood donors: common and rare alleles.Molecular biology reports · 2025Article
- Duration of hemolysis among infants with hemolytic disease of the fetus and newborn.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Alloimmunization to low and high prevalence blood group antigens: rare causes of hemolytic disease of the fetus and newborn.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Late vs. early intrauterine blood transfusion in fetal anemia: impact on maternal and neonatal outcomes.Frontiers in medicine · 2025Article
- B Cell Responses to the Placenta and Fetus.Annual review of pathology · 2025Review
- RH gene inversion-recombination as a major mechanism of the D phenotype in China.Blood transfusion = Trasfusione del sangueArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hemolytic disease of the fetus and newborn (HDFN) can occur when a pregnant woman has antibody directed against an erythrocyte surface antigen expressed by her fetus. This alloimmune disorder is restricted to situations where transplacental transfer of maternal antibody to the fetus occurs, and binds to fetal erythrocytes, and significantly shortens the red cell lifespan. The pathogenesis of HDFN involves maternal sensitization to erythrocyte "non-self" antigens (those she does not express). Exposure of a woman to a non-self-erythrocyte antigen principally occurs through either a blood transfusion or a pregnancy where paternally derived erythrocyte antigens, expressed by her fetus, enter her circulation, and are immunologically recognized as foreign. This review focuses on the genetics, structure, and function of the erythrocyte antigens that are most frequently involved in the pathogenesis of alloimmune HDFN. By providing this information we aim to convey useful insights to clinicians caring for patients with this condition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.