ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2023
Knees with anteromedial osteoarthritis show a substantial phenotypic variation prior and following medial unicompartmental knee arthroplasty.
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Does the preoperative CPAK classification influence clinical outcomes after medial and lateral unicompartmental knee arthroplasty? Short-term outcomes and phenotype distribution in a retrospective series of consecutive cases.Archives of orthopaedic and trauma surgery · 2026Article
- Effect of Coronal Plane Knee Alignment Classification on Clinical Outcomes After High Tibial Osteotomy.Orthopaedic journal of sports medicine · 2026Article
- Postoperative Functional Mobility and Quality of Life in Patients with Anteromedial Osteoarthritis of the Knee Treated with MB-UKA versus TKA.Journal of pain research · 2026Article
- Magnetic resonance imaging provides additional utility in the preoperative cartilage assessment of patients undergoing medial unicompartmental knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Optimizing uni-compartmental knee arthroplasty: the impact of preoperative planning and arithmetic hip-knee-ankle angle.BMC musculoskeletal disorders · 2025Article
- Current evidence on medial unicompartmental knee arthroplasty in patients 60 and younger: a narrative review.Annals of joint · 2025Review
- Restoration of preoperative tibial alignment improves functional results after medial unicompartmental knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
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Abstract
purposeThe primary aim of this study was to evaluate the phenotypic variation using the Coronal Plane Alignment of the Knee (CPAK) classification among 1000 knees with anteromedial osteoarthritis (OA) both prior to and following medial unicompartmental knee arthroplasty (UKA). The secondary aim of this study was to investigate whether knees maintained their preoperative CPAK phenotype and to evaluate the phenotypic alterations following medial UKA.
methodsThe CPAK classification was used to analyze 1000 knees that underwent medial UKA as treatment for anteromedial OA. Knees were categorized into nine distinct CPAK phenotypes based on their arithmetic hip-knee-ankle angle (aHKA), which estimates the pre-arthritic alignment, and joint line obliquity (JLO), both pre- and postoperatively. Phenotypic variation was analyzed by sex and age, and the phenotypic alterations following medial UKA were evaluated by phenotype.
resultsPreoperatively, CPAK phenotype I had the highest prevalence (45.0%). Among males, the preoperative prevalence of CPAK phenotype I was significantly higher compared to females (53.2% vs. 35.0%, respectively; p ≤ .001), whereas females exhibited a significantly higher occurrence of CPAK phenotype V compared to males (9.8% vs. 4.4%, respectively; p ≤ .015). Following medial UKA, CPAK phenotype II had the highest prevalence (53.3%). Overall, 45.1% of knees maintained their preoperative CPAK phenotype following medial UKA, which was most frequently observed among CPAK phenotype II (67.7%) and III (65.8%).
conclusionThere is a substantial variation in CPAK phenotypes among knees with anteromedial OA, as well as following treatment with medial UKA. This variability challenges the assumption of uniform characteristics among knees with an identical wear pattern associated with anteromedial OA and emphasizes the complexity and variability of this specific form of OA. LEVEL OF EVIDENCE: III, Retrospective cohort study.
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