Evidence map›Paper›PMID 37848506›Full record

ArticleScientific reports2023

From himachalenes to trans-himachalol: unveiling bioactivity through hemisynthesis and molecular docking analysis.

A Faris, Y Edder, I Louchachha, I Ait Lahcen, K Azzaoui, B Hammouti, M Merzouki, A Challioui, B Boualy, A Karim and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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  11. Alzheimer's disease:Current research in toxicology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

A FarisEquipe de Chimie de Coordination et Catalyse, Département de Chimie, Faculté des Sciences Semlalia, Université Cadi Ayyad, B.P. 2390, 40001, Marrakech, Morocco. abdelmajid.faris@edu.uca.ac.ma.
Y EdderEquipe de Chimie de Coordination et Catalyse, Département de Chimie, Faculté des Sciences Semlalia, Université Cadi Ayyad, B.P. 2390, 40001, Marrakech, Morocco.
I LouchachhaEquipe de Chimie de Coordination et Catalyse, Département de Chimie, Faculté des Sciences Semlalia, Université Cadi Ayyad, B.P. 2390, 40001, Marrakech, Morocco.
I Ait LahcenEquipe de Chimie de Coordination et Catalyse, Département de Chimie, Faculté des Sciences Semlalia, Université Cadi Ayyad, B.P. 2390, 40001, Marrakech, Morocco.
K AzzaouiLaboratory of Engineering, Electrochemistry, Modeling and Environment, Faculty of Sciences, Sidi Mohamed Ben Abdellah University, 30000, Fez, Morocco.
B HammoutiEuro-Mediterranean University of Fes, B.P. 15, 30070, Fez, Morocco.
M MerzoukiLaboratoire de Chimie Appliquée et Environnement - Equipe Chimie Organique Macromoléculaire et Phytochimie, Faculté des Sciences, Université Mohammed Ier, 60000, Oujda, Morocco.
A ChalliouiLaboratoire de Chimie Appliquée et Environnement - Equipe Chimie Organique Macromoléculaire et Phytochimie, Faculté des Sciences, Université Mohammed Ier, 60000, Oujda, Morocco.
B BoualyEnvironmental Sciences and Applied Materials Research Team, Multidisciplinary Research and Innovation Laboratory, Polydisciplinary Faculty of Khouribga, Sultan Moulay Slimane University of Beni Mellal, B.P. 145, 25000, Khouribga, Morocco.
A KarimEquipe de Chimie de Coordination et Catalyse, Département de Chimie, Faculté des Sciences Semlalia, Université Cadi Ayyad, B.P. 2390, 40001, Marrakech, Morocco.
G HanbaliEquipe de Chimie de Coordination et Catalyse, Département de Chimie, Faculté des Sciences Semlalia, Université Cadi Ayyad, B.P. 2390, 40001, Marrakech, Morocco.
S JodehDepartment of Chemistry, An-Najah National University, P.O. Box 7, Nablus, Palestine. sjodeh@najah.edu.
Cadi Ayyad University · MAAn-Najah National University · PSEuro-Mediterranean University of Fes · MAMohamed I University · MASidi Mohamed Ben Abdellah University · MAUniversité Hassan II Mohammedia · MAUniversité Sultan Moulay Slimane · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we report the first total hemisynthesis of trans-himachalol sesquiterpene, a stereoisomer of the natural cis-himachalol isolated from Cedrus atlantica essential oils, from himachalenes mixture in five steps. Reactions conditions were optimized and structures of the obtained compounds were confirmed by IR, mass spectra,

Indexed as

SesquiterpenesBenzocycloheptenesMolecular Docking SimulationNeurotransmitter AgentsPolycyclic SesquiterpenesBenzocyclohepteneshimachalenehimachalolNeurotransmitter AgentsPolycyclic SesquiterpenesSesquiterpenes

Identifiers

PMID37848506
PMCPMC10582069
OpenAlexW4387694271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.