Evidence map›Paper›PMID 37848295›Full record

ArticleBMJ open2023

Prognosis of patients with long COVID symptoms: a protocol for a longitudinal cohort study at a primary care referred outpatient clinic in Helsinki, Finland.

Hélène Virrantaus, Helena Liira, Tatiana Posharina, Aleksandra Sulg, Teemu Mäntylä, Mari Kanerva, Sini Laakso, Markku Sainio, Antti Malmivaara, Aki Vuokko and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05699512 (What is the Prognosis of Functional Ability, Symptoms and Quality of Life in Patients That Are Treated in a University Hospital Because Symptoms of Post Covid-19 Condition), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05699512 unknown statusnot on this map

What is the Prognosis of Functional Ability, Symptoms and Quality of Life in Patients That Are Treated in a University Hospital Because Symptoms of Post Covid-19 Condition

TypeobservationalSponsorHelsinki University Central HospitalRan2021 to 2024Enrolled400ConditionsPost Covid-19 ConditionArmsMultiprofessional, tailored rehabilitation
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Hélène VirrantausOutpatient Clinic for Long-Term Effects of COVID-19, Helsinki University Central Hospital, Helsinki, Finland lene294@hotmail.com.ORCID 0000-0001-6044-0217
Helena LiiraOutpatient Clinic for Long-Term Effects of COVID-19, Helsinki University Central Hospital, Helsinki, Finland.
Tatiana PosharinaOutpatient Clinic for Long-Term Effects of COVID-19, Helsinki University Central Hospital, Helsinki, Finland.
Aleksandra SulgOutpatient Clinic for Long-Term Effects of COVID-19, Helsinki University Central Hospital, Helsinki, Finland.
Teemu MäntyläOutpatient Clinic for Long-Term Effects of COVID-19, Helsinki University Central Hospital, Helsinki, Finland.
Mari KanervaDepartment of Hospital Hygiene and Infection Control, TYKS Turku University Hospital, Turku, Finland.
Sini LaaksoClinical Neurosciences, Neurology, Helsinki University Central Hospital, Helsinki, Finland.
Markku SainioOutpatient Clinic for Functional Disorders, Helsinki University Central Hospital, Helsinki, Finland.
Antti MalmivaaraCentre for Health and Social Economics, National Institute for Health and Welfare, Helsinki, Finland.ORCID 0000-0002-9042-4450
Aki VuokkoOccupational Medicine, Finnish Institute of Occupational Health, Helsinki, Finland.
Mikko VaronenOutpatient Clinic for Long-Term Effects of COVID-19, Helsinki University Central Hospital, Helsinki, Finland.
Mikko VenäläinenDepartment of Medical Physics, University of Turku, Turku, Finland.ORCID 0000-0003-1777-4259
Jari ArokoskiDepartment of Physical and Rehabilitation Medicine, Helsinki University Central Hospital, Helsinki, Finland.
Helsinki University Hospital · FIFinnish Institute for Health and Welfare · FIFinnish Institute of Occupational Health · FITurku University Hospital · FIUniversity of Helsinki · FIUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAfter COVID-19, many continue to experience persistent debilitating symptoms, that is, long COVID. Its most prevalent symptoms are chest pain, difficulties with breathing, painful muscles, ageusia or anosmia, tingling extremities and general tiredness. This paper describes the protocol of the Long COVID Cohort Study to assess the prognosis and prognostic determinants of patients with long COVID by implementing patient-reported outcome measures (PROMs), patient-reported experience measures (PREMs) and clinical examinations during a 1-year follow-up. METHODS AND ANALYSIS: This is a prospective, single-site cohort study consisting of administering questionnaires and clinical examinations to adult patients referred to the Clinic for Long-Term Effects of COVID-19 at Helsinki University Hospital (Hospital district of Helsinki and Uusimaa). The referrals are from all healthcare units within HUS and other hospital districts during years 2021-2023. All admitted patients have had laboratory-confirmed COVID-19. The targeted study sample size is 500 participants. The questionnaires are administered at 0, 3, 6 and 12 months. The main outcome variables are the changes in self-reported functional abilities and quality of life. In addition, we will evaluate functional abilities at baseline using neurocognitive evaluation, a 6MWT and a measurement of hand grip strength. The Long COVID Cohort Study will form a quality register for the clinic and characterise the first systematic collection of PROMs, PREMs, questionnaire and clinical examinations related to long COVID in Finland. The Study belongs to a study consortium Long COVID-HORIZON-HLTH-2021-DISEASE-04 that aims to reveal the biomechanisms of long COVID. ETHICS AND DISSEMINATION: This study has been approved by the Helsinki University Hospital research ethics committee board, ID HUS/1493/2021 on 6 March 2021. All study participants sign written informed consent for participation. The study findings will be reported for publication in peer-reviewed journals. TRIAL REGISTRATION NUMBER: NCT05699512; Pre-results.

Indexed as

COVID-19AdultAmbulatory Care FacilitiesCohort StudiesFinlandHand StrengthHumansLongitudinal StudiesPost-Acute COVID-19 SyndromePrimary Health CarePrognosisProspective StudiesQuality of LifeSARS-CoV-2Treatment OutcomeCOVID-19PrognosisQuality of LifeREHABILITATION MEDICINE

Identifiers

PMID37848295
PMCPMC10582861
OpenAlexW4387729049

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.