ArticleAmerican journal of perinatology2024
Prognostic Relevance of the Lung Ultrasound Score: A Multioutcome Study in Infants with Respiratory Distress Syndrome.
Article in American journal of perinatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.
- Characteristics of scores used for quantitative lung ultrasound in neonates: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Diagnostic accuracy of lung ultrasound score for bronchopulmonary dysplasia in preterm neonates: a systematic review and meta-analysis.Frontiers in pediatrics · 2025Pooled it
- Current Clinical Perspectives of Biomarkers in Respiratory Diseases: A Narrative Review.Journal of clinical medicine · 2026Review
- An End-to-end Interactive Software for Pediatric Pneumonia Severity Assessment from Lung Ultrasound Images.Ultrasound international open · 2026Article
- Early lung ultrasound score combined with umbilical cord-blood procalcitonin improves 1-year prognostic stratification in preterm neonates with respiratory distress syndrome.Frontiers in pediatrics · 2026Article
- An elegant review - but a complicated bedside? Rethinking dual protocols for neonatal lung ultrasound.European respiratory review : an official journal of the European Respiratory Society · 2025Article
- ESICM-ESPNIC international expert consensus on quantitative lung ultrasound in intensive care.Intensive care medicine · 2025Article
- miR-221-3p, arterial blood gas, and lung ultrasound: a multimodal approach for predicting neonatal respiratory distress syndrome outcomes.Journal of cardiothoracic surgery · 2025Article
- Guidelines for the use of lung ultrasound to optimise the management of neonatal respiratory distress: international expert consensus.BMC medicine · 2025Article
- Proportion of confluent B-Lines predicts respiratory support in term infants shortly after birth.Respiratory research · 2024Observational
- Lung Ultrasound Score in Neonatal RDS: Agreement between Sonography Expert and Neonatologists with Varying Levels of Experience.Healthcare (Basel, Switzerland) · 2024Article
- Diagnostic Accuracy of Lung Ultrasound in Neonatal Diseases: A Systematized Review.Journal of clinical medicine · 2024Review
- Descriptive and Functional Genomics in Neonatal Respiratory Distress Syndrome: From Lung Development to Targeted Therapies.International journal of molecular sciences · 2024Review
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThere is growing evidence for the usefulness of the lung ultrasound score (LUS) in neonatal intensive care. We evaluated whether the LUS is predictive of outcomes in infants with respiratory distress syndrome (RDS). STUDY
designNeonates less than 34 weeks of gestational age were eligible for this prospective, multicenter cohort study. The outcomes of interest were the need for mechanical ventilation (MV) at <72 hours of life, the need for surfactant (SF), successful weaning from continuous positive airway pressure (CPAP), extubation readiness, and bronchopulmonary dysplasia. Lung scans were taken at 0 to 6 hours of life (Day 1), on Days 2, 3, and 7, and before CPAP withdrawal or extubation. Sonograms were scored (range 0-16) by a blinded expert sonographer. The area under the receiver operating characteristic curve (AUC) was used to estimate the prediction accuracy of the LUS.
resultsA total of 647 scans were obtained from 155 newborns with a median gestational age of 32 weeks. On Day 1, a cutoff LUS of 6 had a sensitivity (Se) of 88% and a specificity (Sp) of 79% to predict the need for SF (AUC = 0.86), while a cutoff LUS of 7 predicted the need for MV at <72 hours of life (Se = 89%, Sp = 65%, AUC = 0.80). LUS acquired prior to weaning off CPAP was an excellent predictor of successful CPAP withdrawal, with a cutoff level of 1 (Se = 67%, Sp = 100%, AUC = 0.86).
conclusionThe LUS has significant predictive ability for important outcomes in neonatal RDS. KEY POINTS: · Lung ultrasound has significant prognostic abilities in neonatal RDS.. · Early sonograms (0-6 h of life) accurately predict the requirement for SF and ventilation.. · Weaning off CPAP is effective when the LUS (range 0-16) is less than or equal to 1..
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Registered trials
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